Welcome to our Blog

The Good, the Bad and the Ugly Side of the Gut Microbiome
Kimberley Bryon-Dodd
Jul 10, 2018
This blog takes a look at recent research on gut microbiota and immunotherapy response, and how this knowledge could be used to predict response or improve response rates.
Pigging up the Pace of Influenza A Vaccine Development
Kimberley Bryon-Dodd
Jun 27, 2018
Developing a universal flu vaccine that delivers broad protection against influenza is highly desirable, especially in context of pandemics. A groundbreaking discovery in Babraham pigs has significantly improved its usefulness as an immunological model and could greatly advance vaccine research.
Checkmate: Beating Cancer through the PD-1 Pathway
Kimberley Bryon-Dodd
Jun 19, 2018
Immunotherapy works by enhancing the host immune system to more effectively detect and kill cancer cells. This blog discusses the PD-1 (programmed cell death-1) pathway and two licensed immunotherapy drugs that target it, pembrolizumab and nivolumab.
Th2A Cells — the Latest T Helper Cell Subset and its Role in Allergy
May 16, 2018
Th2A cells are a recently identified subset of T helper cells type 2 (Th2). This blog looks at the role of Th2A cells in allergy.
Getting the Dose Right
Kimberley Bryon-Dodd
May 14, 2018
Suffering from a chronic condition can mean constant treatment for an extended period of time. This blog discusses therapeutic drug monitoring and why it is used for conditions such as IBD to ensure that treatment remains safe and effective.
Inking the Immune System: How Macrophages Make Tattoos Last
Kimberley Bryon-Dodd
Apr 04, 2018
Baranska et al. (2018) identify macrophage dynamics as being key to tattoos lasting in their recent study. This blog examines the paper in more detail and why tattoos are so difficult to remove.
How to Get More Out of Your Multicolor Panels
Kimberley Bryon-Dodd
Mar 13, 2018
This blog post explains how to build better panels for flow cytometry through optimizing for antigen density, using a dump channel and including viability markers.
SUMOylation: a Heavyweight in the Regulation of Cell Cycle Progression and Cell Proliferation – Part Two
Feb 13, 2018
In the second part of our series on SUMOylation, we examine how key cell signaling proteins are regulated by SUMOylation, the effect of their aberrant SUMOylation on signaling pathways and the potential of SUMO inhibitors in cancer therapy.