Developing a universal flu vaccine that delivers broad protection against influenza is highly desirable, especially in context of pandemics. A groundbreaking discovery in Babraham pigs has significantly improved its usefulness as an immunological model and could greatly advance vaccine research.
Immunotherapy works by enhancing the host immune system to more effectively detect and kill cancer cells. This blog discusses the PD-1 (programmed cell death-1) pathway and two licensed immunotherapy drugs that target it, pembrolizumab and nivolumab.
Suffering from a chronic condition can mean constant treatment for an extended period of time. This blog discusses therapeutic drug monitoring and why it is used for conditions such as IBD to ensure that treatment remains safe and effective.
In the second part of our series on SUMOylation, we examine how key cell signaling proteins are regulated by SUMOylation, the effect of their aberrant SUMOylation on signaling pathways and the potential of SUMO inhibitors in cancer therapy.