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SUMOylation: a Heavyweight in the Regulation of Cell Cycle Progression and Cell Proliferation – Part Two
Bio-Rad
Feb 13, 2018
In the second part of our series on SUMOylation, we examine how key cell signaling proteins are regulated by SUMOylation, the effect of their aberrant SUMOylation on signaling pathways and the potential of SUMO inhibitors in cancer therapy.
SUMOylation: a Heavyweight in the Regulation of Cell Cycle Progression and Cell Proliferation – Part One
Bio-Rad
Feb 09, 2018
In the first part of our two-part series on SUMOylation we discuss the discovery of SUMO and the importance of SUMOylation in cell cycle regulation and cellular proliferation.
Why EGF R is an Attractive Target for Cancer Therapy
Kimberley Bryon-Dodd
Jan 15, 2018
Epidermal growth factor receptor (EGF R) is the most extensively studied receptor tyrosine kinase. In this blog we examine the history of EGF R, the EGF R family and its function along with how EGF R promotes cancer development.
The underlying reason beta cells fail to proliferate in “diabesity” uncovered
Bio-Rad
Aug 21, 2017
Diabesity refers to the link between obesity and type 2 diabetes. This blog post describes the latest scientific findings describing the mechanism behind the failure of beta cells to proliferate in patients with type 2 diabetes, which could lead to novel treatments for this disease.
The possible autoimmune nature of Parkinson’s disease is linked to variant MHC class II alleles
Annalise Barnette
Jul 20, 2017
Discover new studies describing the auto-immune mechanism associated with the development of Parkinson's Disease.
How good bacteria protect us from pathogenic infection
Annalise Barnette
Jul 10, 2017
This blog post describes seminal studies demonstrating the beneficial role of commensal bacteria in treating microbial infections and addressing antibiotic resistance.
Rats — An ideal animal model of human disease
Annalise Barnette
Jun 21, 2017
Discover the distinct features of rats that make them ideal animal models for scientific research as well as new discoveries generated using transgenic rat models.
How to identify major immune cell types by their CD marker expression
Bio-Rad
May 19, 2017
Knowing what markers to use to identify certain immune cell types can be confusing and time-consuming. This blog post describes a new tool from Bio-Rad that simplifies this process for the most common immune cell types.