Blog Topic: Cancer
Iron and Ferroptosis: A Hidden Barrier to CAR T-Cell Function
This blog discusses how iron affects CAR T cells, why ferroptosis may contribute to CAR T-cell dysfunction, and what this could mean for improving cancer immunotherapy.
- Oct 09, 2026
- 3 min read
- Jey Alagarsamy
How Lung Tumors Hijack Nerves to Dodge the Immune System
In this blog, we discuss a recent paper by Wei et al. (2026), which uncovered a new mechanism by which tumor cells use the nervous system to bolster their position in the body.
- May 29, 2026
- 4 min read
- Chloe Fenton, PhD
Let Sleeping Cells Lie: How Immune Cells Influence Metastatic Dormancy
In this blog, we discuss how flow cytometry was used to examine metastatic dormancy, revealing a new role for immune cells in regulating this process.
- Mar 25, 2026
- 4 min read
- Chloe Fenton, PhD
ADP-Ribosylation — A PARful Regulator of the Cell
In this blog, we explore the intricate role of ADP-ribosylation in health and disease.
- Nov 27, 2025
- 4 min read
- Chloe Fenton, PhD
Cell Cannibalism: How Entosis Shapes Cancer
Why do some cells eat their neighbors alive? Explore entosis, the form of cell cannibalism found in many tumors, and whether it helps or hinders cancer.
- Oct 24, 2025
- 3 min read
- Chloe Fenton, PhD
CAR T-Cell Therapy — Driving the Future of Cancer Treatment
In this blog, we discuss a recent study that used CAR T-cell therapy in a subset of gastric cancer patients
- Sep 16, 2025
- 3 min read
- Sindhu Nair, PhD
The Role of Regulatory T Cells in the Fight against Lung Cancer
In this blog, we discuss a recent paper studying the effect of depleting Tregs in lung cancer treatment.
- Apr 23, 2025
- 5 min read
- Bio-Rad
Bispecific Antibodies: A New-Age Cancer Immunotherapy to Battle Solid Tumors
In this blog, we discuss how bsAbs are gaining traction as a novel treatment strategy for NSCLC and showing great promise in combination therapy in clinical trials.
- Feb 21, 2025
- 4 min read
- Bio-Rad
Could Salmonella Be Our Unlikely Ally in the Fight against Cancer?
In this blog, we discuss recent advances in bacterial cancer therapy (BCT).
- Jan 31, 2025
- 4 min read
- Chloe Fenton, PhD
Tumor Patrol: Dendritic Cells in Anti-Tumor Immunity
In this blog, we discuss new insights about how DCs control immune responses in the tumor microenvironment and the implications for immunotherapy.
- Aug 27, 2024
- 4 min read
- Sindhu Nair, PhD
Monoclonal Antibodies for the Treatment of Endometrial Cancer
In this blog, we discuss the recent approval of dostarlimab (Jemperli), a PD-1 inhibitor, in combination with chemotherapy as a first-line treatment for endometrial cancer.
- Feb 27, 2024
- 4 min read
- Chloe Fenton, PhD
Can Exercise Boost Anticancer Immunity?
In this blog, we discuss some of the research investigating the beneficial effects of exercise on anticancer immunity.
- Jan 04, 2024
- 5 min read
- Chloe Fenton, PhD
Spot the Difference: Why There Are Two Ways to Develop Melanoma
This blog discusses how both UV radiation and non-UV pathways can promote melanoma.
- Jul 07, 2023
- 5 min read
- Katie Lee
The Buzz Around STING Agonists
This blog gives an overview of the history of the STimulator of Interferon Genes (STING) pathway and highlights why pharmaceutical companies are making a beeline to develop STING agonists.
- Jun 10, 2021
- 4 min read
- Kimberley Bryon-Dodd, PhD
A Balancing AKT: the E17K Hotspot Mutation and How It Defines Cancer
AKT is an extremely important kinase in human health, playing an intricate role in coordinating fundamental signaling pathways. This blog discusses a “hotspot” mutation, called E17K, that can cause constant AKT activation and wreak havoc on cell homeostasis.
- Apr 27, 2021
- 4 min read
- Katie Roberts, PhD
The Importance of Phosphorylation Events in Cancer
This blog discusses phosphorylation, a common regulator of signal transduction pathways and the role of inappropriate phosphorylation events in cancer.
- Oct 11, 2019
- 4 min read
- Kimberley Bryon-Dodd, PhD
Can Medicine Trust Your Gut Organoids?
This blog focuses on gastrointestinal organoids and their role in advancing cancer research and therapy.
- Sep 17, 2018
- 4 min read
- Kimberley Bryon-Dodd, PhD
Inducing macrophages that work against rather than for cancer
Within the immune response to cancer macrophages present both a problem and solution. This post describes how they can assist with tumor clearance.
- Apr 15, 2016
- 2 min read
- Annalise Barnette, PhD