Most Recent
Monoclonal Antibodies for the Treatment of Endometrial Cancer

In this blog, we discuss the recent approval of dostarlimab (Jemperli), a PD-1 inhibitor, in combination with chemotherapy as a first-line treatment f...

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Monoclonal Antibodies for the Treatment of Endometrial Cancer

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Voices of Women in Science: Dr Helen Wright

As part of International Day of Women and Girls in Science, Bio-Rad invites researchers to share their own experiences of being a woman in science. In...

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Voices of Women in Science: Dr Helen Wright

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Can Designer Pigs Improve Xenotransplantation?

In this blog, we will discuss recent advances in the development of transplant-ready pig kidneys as a source of lifesaving organs for ESRD patients.

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Can Designer Pigs Improve Xenotransplantation?

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The Past, the Present, and the Future of Immunoglobulin M

In this blog, we discuss a recent discovery showing that the protein CD5L is associated with immunoglobulin M in the circulation.

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The Past, the Present, and the Future of Immunoglobulin M

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Can Exercise Boost Anticancer Immunity?

In this blog, we discuss some of the research investigating the beneficial effects of exercise on anticancer immunity.

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Can Exercise Boost Anticancer Immunity?

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Insights From Immunologists: Professor Lynn Morris

We spoke to Professor Lynn Morris about her impressive scientific career, from working on F4/80 in Professor Gordon’s lab as a student to her signific...

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Insights From Immunologists: Professor Lynn Morris

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No Guts, No Glory: Innovative Treatments for Crohn’s Disease

In this blog, we will discuss the different methods utilized to treat Crohn's disease, including the more commonly used biologics and the newly approv...

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No Guts, No Glory: Innovative Treatments for Crohn’s Disease

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Zombie Slayers: Novel Therapeutics to Kill Senescent Cells in Disease

In this blog, we take a look at a new class of drugs, known as senolytics, that target so-called “zombie” cells and how this provides the potential to...

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Zombie Slayers: Novel Therapeutics to Kill Senescent Cells in Disease

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Puppetry of a Parasite: How Toxoplasma gondii Manipulates its Host

In this blog, we discuss new research from Meyer et al. (2022), suggesting that mild manipulation from T. gondii increases a gray wolf’s risk-taking b...

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Puppetry of a Parasite: How Toxoplasma gondii Manipulates its Host

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How Dreams Can Predict Neurodegenerative Disorders

In this blog, we will discuss what RBD is, treatments for the condition, and what is thought to cause it. We will also look at the link between this r...

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How Dreams Can Predict Neurodegenerative Disorders

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Siamon Gordon: The Father of F4/80

In this blog Siamon Gordon tells us about his life and career, with an impressive scientific pedigree and immense contributions to macrophage research...

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Siamon Gordon: The Father of F4/80

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The TLR7/IRF-5 Axis in HIV: a Matter of Life and Cell Death?

In this blog, we discuss a recent study by Carmona-Pérez et al., in which they investigate the role of the Toll-like receptor (TLR) 7/interferon regul...

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The TLR7/IRF-5 Axis in HIV: a Matter of Life and Cell Death?

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From Powerhouses to Inferno: A Mitochondrial Messenger Fuels Inflammation

In this blog, we discuss the concept of immunometabolism, including a new study published by Hooftman et al. (2023) in Nature showing how a molecule d...

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From Powerhouses to Inferno: A Mitochondrial Messenger Fuels Inflammation

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Spot the Difference: Why There Are Two Ways to Develop Melanoma

This blog discusses how both UV radiation and non-UV pathways can promote melanoma.

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Spot the Difference: Why There Are Two Ways to Develop Melanoma

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Tips for Writing Your Thesis

In this blog we’ve compiled our top tips to make your writing process as easy (or at least tolerable) as possible.

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Tips for Writing Your Thesis

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Go Pig or Go Home: Promising Vaccine Developed Against African Swine Fever

In this blog, we explore the research behind a new potential vaccine against African Swine Fever.

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Go Pig or Go Home: Promising Vaccine Developed Against African Swine Fever

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The Biochemical Basis of Depression

This blog outline what is currently known about depression and anti-depressants, in the context of brain biochemistry.

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The Biochemical Basis of Depression

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Immune Cells Get an Upgrade: A Stronger Defense against Cancer

This blog takes a look at recent advances in CAR T-cell therapies, which allow CAR expression and release of cytokines in a controllable manner.

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Immune Cells Get an Upgrade: A Stronger Defense against Cancer

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Feline Good: FMT Reduces Digestive Problems in Cats

In this blog, we discuss the results and clinical implications of this new study investigating the benefits of FMT in cats.

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Feline Good: FMT Reduces Digestive Problems in Cats

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Erebosis: Fly Guts Die in Darkness

This blog discusses a recently discovered form of regulated cell death known as erebosis, found in the guts of fruit flies.

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Erebosis: Fly Guts Die in Darkness

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Unlocking the Secrets of Neuroimmunology: Connecting What Belongs Together

In this blog, Patrick Penndorf writes about neuroimmunology, the connection between neuroscience and immunology research. This blog was awarded joint ...

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Unlocking the Secrets of Neuroimmunology: Connecting What Belongs Together

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The Marteilia Manifestation

In this blog, Rowan Cox, tells the story of the spread of the Marteilia parasite in cockles. This blog was awarded joint 2nd place in the 2022 Bio-Rad...

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The Marteilia Manifestation

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It Takes a Village: How a Dysfunctional Cellular Community Could Raise a Melanoma

2022 Bio-Rad Science Writing Competition winning article. Katie Lee uses an “it takes a village” analogy to explain how it is the combination of multi...

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It Takes a Village: How a Dysfunctional Cellular Community Could Raise a Melanoma

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2022 Science Writing Competition

Find out who won the 2022 Bio-Rad Science Writing Competition.

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2022 Science Writing Competition

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Voices of Women in Science: Associate Professor Carolyn Carr

As part of International Day of Women and Girls in Science, Bio-Rad invited researchers to share their own experiences of being a woman in science. In...

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Voices of Women in Science: Associate Professor Carolyn Carr

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Meet Philippa Marrack: a Pioneer in T Cell Biology

In this blog, we take a look at the career of Dr Philippa Marrack, an immunologist whose research helped shed light on T cell development and functio...

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Meet Philippa Marrack: a Pioneer in T Cell Biology

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Compliance-Ready Flow Cytometry with the ZE5 Cell Analyzer

At Bio-Rad, we recognize the need for cutting-edge flow cytometry at all stages of the drug discovery process, so we have partnered with Xybion to pr...

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Compliance-Ready Flow Cytometry with the ZE5 Cell Analyzer

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Is it Time to Upgrade Your Flow Cytometer?

In this blog, we outline some of the considerations for whether it is time to upgrade your flow cytometer.

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Is it Time to Upgrade Your Flow Cytometer?

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Dogs: Wolves in Sheep’s Clothing?

This blog takes a look at a study by Bergström et al. that examined the DNA from ancient wolves to help answer the origins of dogs from wolf populatio...

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Dogs: Wolves in Sheep’s Clothing?

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Zombie Viruses That Come Back From the Dead

This blog discusses viruses like herpes simplex and hepatitis B, that like a zombie return once you think they have been defeated. 

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Zombie Viruses That Come Back From the Dead

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Myelin: It’s Great to Insulate

In this guest blog, we dive into the structure and function of myelin and the consequences of myelin-associated diseases.

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Myelin: It’s Great to Insulate

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Getting Started in Science Writing and Communication

In this blog, Lab Crunches Editor, Kimberley Bryon-Dodd shares her journey from scientist to science communicator and her top tips for getting started...

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Getting Started in Science Writing and Communication

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Placenta or Pleasant-a? A Marvelously Alien Organ

In this guest blog, the 2021 Bio-Rad Science Writing Competition Winner, Keira Lee Rice, discusses the placenta.

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Placenta or Pleasant-a? A Marvelously Alien Organ

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Genes, but Backwards: Grist for the Evolutionary Mill

Where do new genes come from? This guest blog by Md Hassan Uz-Zaman discusses this question and how our view on this has evolved over time.

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Genes, but Backwards: Grist for the Evolutionary Mill

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A PITiful End for a Pathogen

In this guest blog, Temitayo Bamgbose, a graduate student at Louisiana State University Health Sciences Center, Shreveport, discusses PITs, a tactic u...

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A PITiful End for a Pathogen

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Mucins: the Snot so Glamorous Future of Medicine?

In this guest blog, Katie Lowles discusses mucins, proteins that form protective mucous barriers in epithelial cells, and recent research highlighting...

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Mucins: the Snot so Glamorous Future of Medicine?

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Could Genetically-Modified Pigs Be the Future of Xenotransplantation?

This blog discusses xenotransplantation, the groundbreaking experimental procedure, where a man with end stage heart failure received a donor heart fr...

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Could Genetically-Modified Pigs Be the Future of Xenotransplantation?

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350+ Ways pRB is More than Just E2F Regulation

In this guest blog, Sabine Hahn, a researcher who focuses on the dynamic regulation of chromatin structure and how that influences chromosome segregat...

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350+ Ways pRB is More than Just E2F Regulation

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The Cancer-Therapy Arms Race

In this guest blog, Grace Gregory discusses Non-small Cell Lung Cancer (NSCLC), some of the different treatment approaches being used, and why finding...

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The Cancer-Therapy Arms Race

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Treat Them Right! – Best Practices for Storing and Working with Antibodies

This blog discusses some best practices for storing and using your antibodies to get the most out of them in your experiments.

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Treat Them Right! – Best Practices for Storing and Working with Antibodies

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What Makes Us Tick?

In this guest blog, Katie Lowles discusses the circadian clock and why it is important for human health.

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What Makes Us Tick?

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Genetically Engineered Pigs to Fight Disease

In this blog, we discuss Porcine Reproductive and Respiratory Syndrome (PRSS)-resistant pigs and how this could help alleviate the economic burden of ...

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Genetically Engineered Pigs to Fight Disease

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The Training Bench: Workout Your Immunoprecipitation Fitness Goals

If your IP technique is something that you are trying to improve, this blog has advice to help you to get better immunoprecipitation results.

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The Training Bench: Workout Your Immunoprecipitation Fitness Goals

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The Importance of Antibody Validation

In this blog, we discuss the importance of antibody validation and highlight steps you can take to ensure you generate publication-quality data.

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The Importance of Antibody Validation

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6 Steps for Success with Multicolor Flow Cytometry

In this blog, we cover some key considerations for multicolor flow cytometry panel design, and highlight handy tools to help you get great results fro...

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6 Steps for Success with Multicolor Flow Cytometry

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Secrets of Aging

In this guest blog for Lab Crunches, Shermaine Thein explores the concept of aging and why how old we are may not be as simple as just a number.

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Secrets of Aging

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Gamma Delta T cells: The Unsung Heroes of Immunology

This blog was awarded 3rd place in the 2021 Bio-Rad Science Writing Competition.

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Gamma Delta T cells: The Unsung Heroes of Immunology

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Thoughts of Mice: Understanding the Role Serotonin Plays in Cognitive Flexibility

This blog was awarded 2nd place in the 2021 Bio-Rad Science Writing Competition.

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Thoughts of Mice: Understanding the Role Serotonin Plays in Cognitive Flexibility

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Macrophages May Explain Tuberculosis Tropism

In this blog, we discuss new research that reveals how M. bovis manipulates bovine, but not human, macrophage defenses to cause disease, and helps exp...

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Macrophages May Explain Tuberculosis Tropism

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"Fin"tech: Zebrafish Models

The winning submission in the 2021 Bio-Rad Science Writing Competition.

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"Fin"tech: Zebrafish Models

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2021 Science Writing Competition Results

Find out who won the 2021 Bio-Rad Science Writing Competition.

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2021 Science Writing Competition Results

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What Causes Alzheimer’s Disease?

In this guest blog, we summarize some of the various hypotheses that have been proposed over the years for the development of Alzheimer's diseases, an...

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What Causes Alzheimer’s Disease?

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The Buzz Around STING Agonists

This blog gives an overview of the history of the STimulator of Interferon Genes (STING) pathway and highlights why pharmaceutical companies are makin...

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The Buzz Around STING Agonists

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Could an Unconventional Vaccine Program Prove a Roaring Success?

This blog highlights the threat that canine distemper virus poses to the Amur tiger and discusses whether vaccinating these tigers could help protect ...

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Could an Unconventional Vaccine Program Prove a Roaring Success?

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An Introduction to Spectral Flow Cytometry

This blog highlights the basic principles of spectral flow cytometry and some of its advantages over conventional flow cytometry.

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An Introduction to Spectral Flow Cytometry

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A Balancing AKT: the E17K Hotspot Mutation and How It Defines Cancer

AKT is an extremely important kinase in human health, playing an intricate role in coordinating fundamental signaling pathways. This blog discusses a ...

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A Balancing AKT: the E17K Hotspot Mutation and How It Defines Cancer

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Impostor Syndrome: Being a Graduate Student in the Sciences

This guest blog discusses impostor syndrome in graduate school and practical steps you can take to combat these feelings.

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Impostor Syndrome: Being a Graduate Student in the Sciences

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Big Dreams: Multidisciplinary Science — Not a Fairytale

In this guest blog, Christine Lalonde, a Postdoctoral Fellow at Laurentian University, Canada, shares her experience of a multidisciplinary research c...

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Big Dreams: Multidisciplinary Science — Not a Fairytale

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Unlocking the Mechanism of a Deadly Infection in Pigs

This blog discusses a paper published in Cell Host and Microbe by Bruggisser et al. (2020) that shows that CD31 is crucial for C. perfringens pathogen...

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Unlocking the Mechanism of a Deadly Infection in Pigs

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The Transcriptomic Swiss Army Knife— A-to-I RNA Editing

In this guest blog, Priyankaa Pitcheshwar, a PhD student working in the area of adenosine-to-inosine (A-to-I) RNA editing in the context of cancer, te...

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The Transcriptomic Swiss Army Knife— A-to-I RNA Editing

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Can COVID-19 Trigger New-Onset Diabetes?

In this guest blog, Janielle Cuala, tells us about an interesting link between COVID-19 and new-onset diabetes and the research her lab is doing in th...

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Can COVID-19 Trigger New-Onset Diabetes?

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How Do Pattern Recognition Receptors Help Mount an Immune Response?

This guest blog takes a look at pattern recognition receptors and how they mount an immune response against viruses.

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How Do Pattern Recognition Receptors Help Mount an Immune Response?

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How to Use Flow Cytometry to Measure Apoptosis: Part Two

Design robust experiments and troubleshoot existing protocols for measuring apoptosis by flow cytometry, by following the advice in this blog.

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How to Use Flow Cytometry to Measure Apoptosis: Part Two

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My PhD Love Affair

Guest contributor, Marta González-Prieto shares her love story with her PhD project and how despite initial challenges they eventually got the happy e...

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My PhD Love Affair

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Looking Beneath the Surface: Viral Clearance by Anti-Nucleoproteins

This guest blog examines a paper published by Caddy et al. (2020) in EMBO Journal that sheds new light on anti-nucleoprotein antibodies and clearance ...

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Looking Beneath the Surface: Viral Clearance by Anti-Nucleoproteins

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Voices of Women in Science: Assistant Professor Lynda Coughlan

As part of International Day of Women and Girls in Science, Bio-Rad invited researchers to share their own experiences of being a women in science. In...

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Voices of Women in Science: Assistant Professor Lynda Coughlan

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Voices of Women in Science: Professor Sara Mole

As part of International Day of Women and Girls in Science, Bio-Rad invited researchers to share their own experiences of being a women in science. In...

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Voices of Women in Science: Professor Sara Mole

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Voices of Women in Science: Olivia Blondheim

As part of International Day of Women and Girls in Science, Bio-Rad invited researchers to share their own experiences of being a women in science. In...

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Voices of Women in Science: Olivia Blondheim

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How to Use Flow Cytometry to Measure Apoptosis: Part One

Learn about the different tools for studying apoptosis by flow cytometry and how to use them to get the best results.

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How to Use Flow Cytometry to Measure Apoptosis: Part One

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A T Cell for Your Thoughts?

Can T cells influence our brain function? In this guest blog, we explore the contribution of T cells to learning and memory.

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A T Cell for Your Thoughts?

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The PhD: More than a Thesis

In this guest blog, Emma Green tells us why the value of a PhD is more than just your research and what she learned from the experience.

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The PhD: More than a Thesis

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How CRISPR Revolutionized Science

This blog discusses the CRISPR technology that was awarded the 2020 Nobel Prize in Chemistry.

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How CRISPR Revolutionized Science

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Pokemon Antibody - I Choose You

Bio-Rad has searched through our catalog to show you some of our antibodies with hilarious names from Pokemon to dinosaurs.

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Pokemon Antibody - I Choose You

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A MASTer Immune cell

In this guest blog, we take a look at some of the areas outside of allergy that mast cells play a role in.

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A MASTer Immune cell

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Tips to Help You Succeed When You Have to Switch PhD Project

Guest contributor Zill-e-Anam Shares her tips for staying on track when you have to switch PhD project, for reasons outside of your control.

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Tips to Help You Succeed When You Have to Switch PhD Project

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3 Reasons to Use alamarBlue In Your Cell Proliferation Studies

In this blog, we will explain what alamarBlue is and how it works, and then explore three main benefits of this reagent.

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3 Reasons to Use alamarBlue In Your Cell Proliferation Studies

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Lessons from the Pandemic: How to Be a Good Lab Mate

In this guest blog, Sabine shares the research challenges caused by the pandemic and how her lab has implemented small changes to how they work for th...

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Lessons from the Pandemic: How to Be a Good Lab Mate

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How to Pull-Down Your Target Protein and Interactors Successfully

This blog will take you through the basics of IP so you can get successful results from the outset.

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How to Pull-Down Your Target Protein and Interactors Successfully

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Secrets of the Haunted Brain: Ghost Tangles

In this guest blog, we discuss ghost tangles, the remains of tau (found after neuronal death), and their effects.

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Secrets of the Haunted Brain: Ghost Tangles

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Hopes to Restore Movement in People with Parkinson’s

In this guest blog, Emma Green discusses why cell replacement therapy may offer hope for restoring movement in people with Parkinson's Disease.

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Hopes to Restore Movement in People with Parkinson’s

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An Age Old Question

In this blog, guest contributor Shermaine Thein shares some of the insights that she has learned about aging as a graduate student stepping into the r...

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An Age Old Question

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How to Avoid Cell Stress While Cell Sorting

This blog describes the forces that cells undergo during sorting, and practical steps you can take to minimize cell stress and get great results in yo...

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How to Avoid Cell Stress While Cell Sorting

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The Path to a Nobel Prize

In this blog, we examine why understanding the oxygen sensing mechanisms of cells was worthy of a Nobel Prize and interview Professor Sir Peter Ratcli...

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The Path to a Nobel Prize

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Performing Inclusive Research in the Lab

In this blog, Guest Writer Samantha Zambuto shares her perspective on why it is important that scientists study women’s health.

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Performing Inclusive Research in the Lab

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Seeing SARS – the Remarkable Story of June Almeida

This blog takes a look at the career of June Almeida, who became a pioneer in the imaging and identification of viruses.

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Seeing SARS – the Remarkable Story of June Almeida

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Slash the Tires Instead to Slow Down Prostate Cancer

This article was awarded 3rd place in the 2020 Bio-Rad Science Writing Competition.

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Slash the Tires Instead to Slow Down Prostate Cancer

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Out of My Comfort Zone: How I Use Science to Influence Policy

This article was awarded 2nd place in the 2020 Bio-Rad Science Writing Competition.

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Out of My Comfort Zone: How I Use Science to Influence Policy

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Is a Cure for HIV on the Horizon?

This blog discusses the CCR5 co-receptor and the role that it could play in an HIV cure, as well as the patients who appear to be in long-term remissi...

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Is a Cure for HIV on the Horizon?

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Making the Switch to Non-Animal Derived Antibodies

This blog discusses the reasons why non-animal derived recombinant antibodies are something that both antibody suppliers and researchers should consid...

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Making the Switch to Non-Animal Derived Antibodies

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Science Writing Competition Results

The winners of the 2020 Bio-Rad Science Writing Competition are revealed.

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Science Writing Competition Results

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Inspiring Science - Why Public Engagement Is Key

Read the winning article of the 2020 Bio-Rad Science Writing Competition by Alex Du Feu.

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Inspiring Science - Why Public Engagement Is Key

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Could a Monoclonal Antibody Cure COVID-19?

In this blog, we discuss the potential for a monoclonal antibody to neutralize the SARS-CoV-2 virus that causes COVID-19.

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Could a Monoclonal Antibody Cure COVID-19?

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9 Tips to Get Publication Ready Flow Plots

In this blog, our Flow Cytometry Research Associate shares 9 top tips to generate publication-worthy flow plots in a format that reviewers would like ...

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9 Tips to Get Publication Ready Flow Plots

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Navigating the Deadly Cytokine Storm

Sometimes our immune systems launch an excessive, disproportionate response to a real infection, called a "cytokine storm". This blog looks at cytokin...

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Navigating the Deadly Cytokine Storm

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4 Ways to Organize Your Way to Better Science

This blog contains our top tips to help you be more organized and do the best possible science.

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4 Ways to Organize Your Way to Better Science

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Top Tips for Troubleshooting Your BrdU Blues

This blog post focuses on BrdU and top tips and tricks for conducting a BrdU labeling experiment to help you troubleshoot any BrdU blues.

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Top Tips for Troubleshooting Your BrdU Blues

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Keeping Distance from the Lab: 9 Ways to Be Productive

In the wake of the SARS-CoV2 pandemic, social distancing has meant that labs all over the world have needed to temporarily shut. Read our blog on 9 th...

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Keeping Distance from the Lab: 9 Ways to Be Productive

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Diary of a Coronavirologist

Stuart Weston PhD, coronavirologist, shares his insights on what it is like being a researcher in coronaviruses during the 2020 pandemic.

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Diary of a Coronavirologist

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Three Remarkable Women Who Shaped the Antibody Field

International Women’s Day is celebrated on 8th March all over the world to highlight the many achievements of women. To mark the occasion, in this blo...

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Three Remarkable Women Who Shaped the Antibody Field

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The HisTORy behind the Discovery of Rapamycin

This blog tells the story of rapamycin’s discovery, identification of the mTOR signaling pathway, and highlights the important role that basic researc...

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The HisTORy behind the Discovery of Rapamycin

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A Guide to IHC-paraffin Success

This blog is written to help you perfect your IHC-paraffin technique.  It focuses on some of the key stages so that you can achieve publication-qualit...

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A Guide to IHC-paraffin Success

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The Transition from Academia to Industry

Bio-Rad's Flow Cytometry Research Associate, Sharon shares her experience of transitioning from academic research to working in an industry setting in...

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The Transition from Academia to Industry

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New Year's Lab Resolutions

2020 is the start of a new decade. Take inspiration from other scientists and set yourself goals for the year ahead.

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New Year's Lab Resolutions

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Have you got the Festive Factor?

Discover the most festive offerings in our portfolios and their associated “Festive Factor” scores.

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Have you got the Festive Factor?

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Podcast: The Logic Behind Biologic Antibody Drug Names

In this podcast, we explain what International Non-proprietary Names are, and the logic behind their use. 

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Podcast: The Logic Behind Biologic Antibody Drug Names

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ELISAs Do Little? Your Guide to ELISAs Part Two

In this blog, we take a look at sandwich and competitive ELISAs and highlight some of our top ELISA tips.

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ELISAs Do Little? Your Guide to ELISAs Part Two

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ELISAs Do Little? Your Guide to ELISAs Part One

Enzyme-Linked Immunosorbent Assays (ELISAs) are widely used for the detection and quantification of proteins, peptides, hormones, and other substances...

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ELISAs Do Little? Your Guide to ELISAs Part One

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The Importance of Phosphorylation Events in Cancer

This blog discusses phosphorylation, a common regulator of signal transduction pathways and the role of inappropriate phosphorylation events in cancer...

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The Importance of Phosphorylation Events in Cancer

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How to Successfully Manage the PhD-to-Postdoc Transition

In this guest blog, Dr Elisa Vitiello shares her tips on making the transition from being a PhD student to getting your first job in academic research...

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How to Successfully Manage the PhD-to-Postdoc Transition

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WHO Decides What’s INN a Biologics Name?

This blog takes a look at the logic behind the names of monoclonal antibody drugs and implications of the more recent changes in the naming structure....

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WHO Decides What’s INN a Biologics Name?

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Pig Brains and the Gray Matter of Life and Death    

This blog examines new findings that suggest the brain is far more resilient than we have assumed, and that challenge the idea that some functions are...

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Pig Brains and the Gray Matter of Life and Death    

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Taking Control of Your Western Blotting Troubles

This blog discusses the three basic types of controls that should be included in a western blot experiment and provides a good starting point for trou...

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Taking Control of Your Western Blotting Troubles

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Podcast: Studying Cell Proliferation

In this podcast, Bio-Rad reviews three popular methods for studying cell proliferation: using thymidine analogs, quantifying DNA content, and detectin...

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Podcast: Studying Cell Proliferation

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Podcast: Viability Dyes and How to Exclude Dead Cells from Your Analysis

In this podcast, you will learn how to use the different types of viability dyes and exclude dead cells from flow cytometry assays.

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Podcast: Viability Dyes and How to Exclude Dead Cells from Your Analysis

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Podcast: Sample Preparation Tips for Blood Samples

In this podcast, learn how to prepare blood samples ready for flow cytometry experiments with Bio-Rad’s top three tips.

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Podcast: Sample Preparation Tips for Blood Samples

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Tumors Sweet Success due to Macrophage Polarization

This blog discusses a recent study by Bohn et al. (2018) that highlights a mechanism that melanoma utilizes to subvert the immune response.

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Tumors Sweet Success due to Macrophage Polarization

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A.dvancI.ng Scientific Research

This blog highlights how A.I technology is being used to shape scientific discoveries and research direction.

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A.dvancI.ng Scientific Research

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Podcast: The Importance of Cell Frequency

Learn how you can optimize your conditions to improve detection of rare populations by flow cytometry in this podcast from Bio-Rad.

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Podcast: The Importance of Cell Frequency

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Manifestation of Ghosts Exacerbates Asthma

Krishnamoorthy et al. (2018) have identified enucleated neutrophil cell bodies, known as ‘ghosts’, as driving Th17 cell inflammation in severe asthma....

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Manifestation of Ghosts Exacerbates Asthma

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NEWS: Nobel Prizes for the Antibody Field

The 2018 Nobel Prize announcements brought exciting news of two prizes awarded in recognition of ground-breaking achievements in the antibody field.

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NEWS: Nobel Prizes for the Antibody Field

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Can Medicine Trust Your Gut Organoids?

This blog focuses on gastrointestinal organoids and their role in advancing cancer research and therapy.

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Can Medicine Trust Your Gut Organoids?

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SUMOylation: a Heavyweight in the Regulation of Cell Cycle Progression and Cell Proliferation – Part One

This blog post discusses the discovery of SUMO and the importance of SUMOylation in cell cycle regulation and cellular proliferation.

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SUMOylation: a Heavyweight in the Regulation of Cell Cycle Progression and Cell Proliferation – Part One

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Podcast: Studying SUMOylation

Listen to Bio-Rad’s top tips for studying SUMOylation in our podcast.

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Podcast: Studying SUMOylation

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Podcast: BrdU in Adult Neurogenesis Research

Learn Bio-Rad’s practical tips for controlling your BrdU experiments in our podcast.

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Podcast: BrdU in Adult Neurogenesis Research

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Set Yourself up for Success with Flow Cytometry

This blog features some of our top sample preparation tips for flow cytometry and examples of blood and tumor sample preparation.

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Set Yourself up for Success with Flow Cytometry

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The Good, the Bad and the Ugly Side of the Gut Microbiome

This blog takes a look at how gut microbiota may play a role in anti-tumor immune responses.

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The Good, the Bad and the Ugly Side of the Gut Microbiome

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Pigging up the Pace of Influenza A Vaccine Development

Learn more about a groundbreaking discovery in Babraham pigs that has significantly improved its usefulness as an immunological model.

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Pigging up the Pace of Influenza A Vaccine Development

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Checkmate: Beating Cancer through the PD-1 Pathway

This blog discusses the PD-1 (programmed cell death-1) pathway and two licensed immunotherapy drugs that target it, pembrolizumab and nivolumab.

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Checkmate: Beating Cancer through the PD-1 Pathway

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Th2A Cells — the Latest T Helper Cell Subset and its Role in Allergy

Th2A cells are a recently identified subset of T helper cells type 2 (Th2). This blog looks at the role of Th2A cells in allergy.

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Th2A Cells — the Latest T Helper Cell Subset and its Role in Allergy

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Getting the Dose Right

This blog discusses therapeutic drug monitoring and why it is used for conditions such as IBD to ensure that treatment remains safe and effective.

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Getting the Dose Right

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Inking the Immune System: How Macrophages Make Tattoos Last

Baranska et al. (2018) identify macrophage dynamics as being key to tattoos lasting. This blog examines why tattoos are so difficult to remove.

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Inking the Immune System: How Macrophages Make Tattoos Last

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How to Get More Out of Your Multicolor Panels

Learn how to build better panels for flow cytometry through optimizing for antigen density, using a dump channel and including viability markers.

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How to Get More Out of Your Multicolor Panels

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SUMOylation: a Heavyweight in the Regulation of Cell Cycle Progression and Cell Proliferation – Part Two

We examine SUMOylation, the effect of their aberrant SUMOylation on signaling pathways and the potential of SUMO inhibitors in cancer therapy.

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SUMOylation: a Heavyweight in the Regulation of Cell Cycle Progression and Cell Proliferation – Part Two

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Why EGF R is an Attractive Target for Cancer Therapy

We examine the history of Epidermal growth factor receptor (EGF R), the EGF R family and function along with how EGF R promotes cancer development.

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Why EGF R is an Attractive Target for Cancer Therapy

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The underlying reason beta cells fail to proliferate in “diabesity” uncovered

This blog describes scientific findings describing the mechanism behind the failure of beta cells to proliferate in patients with type 2 diabetes

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The underlying reason beta cells fail to proliferate in “diabesity” uncovered

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The possible autoimmune nature of Parkinson’s disease

Discover new studies describing the auto-immune mechanism associated with the development of Parkinson's Disease.

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The possible autoimmune nature of Parkinson’s disease

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How good bacteria protect us from pathogenic infection

This blog describes studies demonstrating the beneficial role of commensal bacteria in treating microbial infections and antibiotic resistance.

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How good bacteria protect us from pathogenic infection

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Rats — An ideal animal model of human disease

Discover the features of rats that make them ideal animal models for scientific research and new discoveries generated using transgenic rat models.

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Rats — An ideal animal model of human disease

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How to identify major immune cell types by their CD marker expression

Learn how a new tool from Bio-Rad simplifies knowing what markers to use to identify certain immune cell types.

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How to identify major immune cell types by their CD marker expression

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Bromodeoxyuridine (BrdU) in adult neurogenesis research - Part 2

Our second part of BrdU in adult neurogenesis research, describes “the dark side of BrdU” and how you can carefully control BrdU labeling experiments...

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Bromodeoxyuridine (BrdU) in adult neurogenesis research - Part 2

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Bromodeoxyuridine (BrdU) in adult neurogenesis research - Part 1

The first of a two part series describing how BrdU revolutionized the field of neurogenesis.

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Bromodeoxyuridine (BrdU) in adult neurogenesis research - Part 1

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Macrophages, obesity and insulin resistance

This blog post describes the mechanisms by which macrophages induce insulin resistance in the obese state.

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Macrophages, obesity and insulin resistance

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What do monocytes have to do with the heart?

This post describes the role of monocytes in heart disease and whether monocyte infiltration into the heart exacerbates disease or aids in its repair....

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What do monocytes have to do with the heart?

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The rise in Zika virus research — an update

This blog post highlights major research findings on ZIKV in 2016, and provides a perspective on how scientists addressed this public health issue.

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The rise in Zika virus research — an update

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Bio-Rad named CiteAb Custom Antibody Supplier of the year!

We are excited to share that Bio-Rad was named as the CiteAb Custom Antibody Supplier of the year.

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Bio-Rad named CiteAb Custom Antibody Supplier of the year!

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A guide to gating in flow cytometry

This blog post will take you through the various gating strategies for effective flow cytometry analysis.

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A guide to gating in flow cytometry

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Illuminating biomedical research — the story of fluorescent proteins

Fluorescent proteins have expanded the capabilities of scientists, thus allowing observations that would not have been possible without them.

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Illuminating biomedical research — the story of fluorescent proteins

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Engineering recombinant inhibitory antibodies as research tools

Researchers partnered with Bio-Rad to engineer high affinity, highly specific inhibitor antibodies to the active site region of a WNV proteinase.

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Engineering recombinant inhibitory antibodies as research tools

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Autophagy, and Neurodegeneration

This blog post highlights autophagy as a therapeutic strategy for neurodegeneration.

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Autophagy, and Neurodegeneration

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Killer bugs among us - the kissing bug and the Asian giant hornet

While insects are not the deadliest animals they can significantly impact human health. Learn about the killer bug and Asian giant hornet.

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Killer bugs among us - the kissing bug and the Asian giant hornet

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The road to antibody validation standards

In this blog post we highlight some the current potholes on the road to reproducible antibodies.

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The road to antibody validation standards

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Applying best practices for characterizing critical reagents

This blog post defines critical reagents and best practices for their characterization.

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Applying best practices for characterizing critical reagents

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Deciding which ELISA technique is right for you

We describe the different types of ELISAs, the advantages and disadvantages of each and what to consider before choosing an ELISA technique.

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Deciding which ELISA technique is right for you

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When ubiquitination goes bad, knock it out for effective cancer therapy

This blog post highlights the key ubiquitin E3 ligases currently considered molecular drug targets.

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When ubiquitination goes bad, knock it out for effective cancer therapy

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The oldest known naturally occurring cancer is transmitted between dogs

Learn more about the biology of the transmissible canine cancer CTVT and why it is a biological curiosity of significant magnitude in this blog post.

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The oldest known naturally occurring cancer is transmitted between dogs

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Monocyte-based cell therapy for treating diseases

This blog post discusses recent pre-clinical studies that suggest monocytes could be applied in a related manner to the treatment of diseases.

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Monocyte-based cell therapy for treating diseases

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Cell death by apoptosis - the journey of a single cell from health to death

This blog describes the triggers & mechanisms that lead to death by apoptosis, as well as assays for measuring apoptosis in your research.

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Cell death by apoptosis - the journey of a single cell from health to death

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Inducing macrophages that work against rather than for cancer

Within the immune response to cancer macrophages present both a problem and solution. This post describes how they can assist with tumor clearance.

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Inducing macrophages that work against rather than for cancer

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The science of keeping pigs healthy

This blog post highlights novel gene-editing strategies to protect pigs against dangerous pathogens.

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The science of keeping pigs healthy

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Biomarker assay development: CXCL10 in HCV infection

HuCAL technology was used to develop high specificity, high affinity antibodies to distinguish between protein isoforms with only minor differences.

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Biomarker assay development: CXCL10 in HCV infection

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5 Easy Steps for Successful Flow Cytometry

In this blog post we simplify the Flow Cytometry process in five easy steps that will ensure successful results.

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5 Easy Steps for Successful Flow Cytometry

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GATA transcription factors and their role in cancer diagnosis and prognosis

The GATA family of transcription factors is emerging as key players in establishing new biomarkers for rapid and accurate detection of cancer. Find ou...

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GATA transcription factors and their role in cancer diagnosis and prognosis

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Immunological memory is no longer a unique trait of adaptive immune cells

The new finding of trained immunity challenges the basic tenets of immunology, blurring the line that separates innate and adaptive immunity.

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Immunological memory is no longer a unique trait of adaptive immune cells

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Zika virus — a new viral threat for 2016?

In this blog post, we describe the history, epidemiology and biology of the Zika virus.

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Zika virus — a new viral threat for 2016?

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High affinity antibodies for improved analysis of antibody drugs

This blog post provides insight on how to improve your assay sensitivity by selecting antibodies based on binding strength as well as affinity.

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High affinity antibodies for improved analysis of antibody drugs

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Journey to the antibody vial: the story of monoclonal antibodies in research

Join us as we take a walk down memory lane and tell the story of how monoclonal antibodies for research purposes came to be.

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Journey to the antibody vial: the story of monoclonal antibodies in research

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How to detect your target protein or protein complex without interfering IgG chains

This blog post discusses TidyBlot and how it does not detect IgG heavy and light chains in your co-IP experiment.

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How to detect your target protein or protein complex without interfering IgG chains

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Does the Ebola virus ever really go away?

This blog post provides an update on the current Ebola epidemic, citing evidence that the virus can linger in immune privileged sites inside the body....

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Does the Ebola virus ever really go away?

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“Is it the antibody?” Tips for caring for your antibody for consistent results

With over 35 years of experience with antibodies, we offer our expert advice for taking care of your antibodies for consistent results.

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“Is it the antibody?” Tips for caring for your antibody for consistent results

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Tailor-made just for you: A future with precision medicine

"There has been a paradigm shift in how the treatment of diseases is approached." This post describes how genome sequencing is revolutionizing the tre...

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Tailor-made just for you: A future with precision medicine

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Immuno-MRM analyses: high-affinity recombinant antibody fragments

This blog post describes the applicability of recombinant antibody fragments from a naive antibody library for immuno-MRM based quantification.

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Immuno-MRM analyses: high-affinity recombinant antibody fragments

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Standardizing Antibody Validation

This blog post describes the current efforts and streams of thought for generating antibody validation standards to address the scientific reproducibi...

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Standardizing Antibody Validation

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Are you likely to develop Alzheimer’s from grilled food?

This blog post describes how your choice of cooking method may increase your risk for developing a range of diseases, including Alzheimer's

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Are you likely to develop Alzheimer’s from grilled food?

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Natural phosphatase inhibitors: the danger around us

This post describes how natural phosphatase inhibitors impact on human health.

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Natural phosphatase inhibitors: the danger around us

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Measuring the inevitable divide - tools for assessing cell proliferation

This post describes crucial markers and useful markers to study aberrant cell proliferation.

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Measuring the inevitable divide - tools for assessing cell proliferation

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Tandem dyes - The power couples of Flow Cytometry

This post describes what tandem dyes are and what to keep in mind when incorporating them into your flow cytometry panels.

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Tandem dyes - The power couples of Flow Cytometry

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Inheriting mutant tumor suppressor genes increases your risk for cancer

This post describes how mutations in proto-oncogenes and tumor suppressor genes account for tumorigenesis.

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Inheriting mutant tumor suppressor genes increases your risk for cancer

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To control or not to control, that is the multi-color flow question…

This post describes what an isotype control is and how one could be beneficial in your multi-color flow cytometry experiments.

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To control or not to control, that is the multi-color flow question…

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Light up your IF experiments with our continued tips and tricks

This post describes selecting fluorophores for your IF experiments based on dye characteristics, such as quantum yields and extinction coefficients.

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Light up your IF experiments with our continued tips and tricks

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Take a quantum leap in your IF experiments with our 5 tips and tricks

This post describes how to choose fluorophores for IF experiments based on dye characteristics, such as quantum yields and extinction coefficients.

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Take a quantum leap in your IF experiments with our 5 tips and tricks

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Four virus serotypes…One Dengue vaccine?

Have a group of researchers really found the key to a cure to the currently incurable Dengue virus? Find out here...

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Four virus serotypes…One Dengue vaccine?

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Intracellular flow cytometry - the good, the bad and the cytokines

This post describes a few key factors to consider when designing intracellular flow cytometry experiments.

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Intracellular flow cytometry - the good, the bad and the cytokines

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10 tips for designing a basic flow cytometry panel

This post provides flow cytometry novices with a basic overview of how to design a multi-color flow cytometry panel.

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10 tips for designing a basic flow cytometry panel

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Flow Cytometry Design Tool

Flow Cytometry Design Tool

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Enroll Now: Free Online Flow Cytometry Course

Enroll Now: Free Online Flow Cytometry Course

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