Innate Immunity Antibodies

Articles

Antibody related mini-reviews, educational summaries and application notes

To help you with your experiments, we have developed a range of useful mini-reviews , educational summaries  and application notes.

This page displays all our antibody related technical and scientific resources. You can access our antibody resources by clicking on the relevant sections.

Recently added:


  1. What is Ebola, outbreaks and current research

An article describing an overview of the Ebola virus, recent outbreaks and Ebola research for future outbreak prevention

  1. Complement system

A mini-review on the complement system, each of its pathways and complement components involved, including a summary on C4d, a known marker of allograft rejection

  1. Neuroinflammation

A mini-review discussing the role of toll like receptors (TLRs) in neuroinflammation, explaining the TLR pathway and TLS in brain cells

 

Featured Product:


PrecisionAb Lab-Validated Antibodies for Western Blotting

PrecisionAb™ Lab-Validated Antibodies for Western Blotting

These antibodies are fully lab-validated using strict testing criteria to deliver superior performance in western blotting detection.

alamarBlue® calculators

alamarBlue® calculators

Bio-Rad exclusively offers two on-line calculators for alamarBlue® generated colorimetric and fluorometric readings. Your raw data can be converted into quantitative results and exported to Excel with a few clicks.

Read our recent blog post on:

Natural phosphatase inhibitors: the danger around us

Phosphatase inhibitors - so much more than research tools

Mini-reviews

These mini-reviews cover a range of research areas with a particular focus on Immunology.

An overview of B cells - from discovery to therapy

An overview of B cells - from discovery to therapy

Mini-review on B cell history, development and activation as well as B cells as therapeutic targets.

CD3 antibody

CD3 antibody mini-review

Overview of the T cell marker CD3, including genes, function and clinical applications for the CD3 protein complex.

Complement system

Complement system mini-review

Mini-review on the complement system, each of its pathways and complement components involved. Includes a summary on C4d, a known marker of allograft rejection.

 

F4/80 antibody

F4/80 antibody mini-review

Mini-review on rat anti-mouse F4/80 antibody (CI:A3-1), providing a technical overview about F4/80 antigen and antibody.

Macrophage polarization

Macrophage polarization mini-review

Mini-review on human and mouse macrophage polarization, and an introduction into macrophage classification and function, including macrophage involvement in cancer.

Monocyte development, characterization and role in disease

Monocyte development, characterization and role in disease

This mini-review characterizes monocytes, providing an overview of their lineage, the classification of the various subsets of monocytes, their function and the role they play in diseases.

Neuroinflammation and Toll-like receptors

Neuroinflammation mini-reviews

Mini-review discussing the role of Toll-like receptors (TLRs) in neuroinflammation, explaining the TLR pathway, and the role of TLRs in brain cells.

NK cells

NK cells mini-review

Mini-review about the natural killer (NK) cell family functions, receptors and cell development in mouse and human.

 

Toll-like receptors (TLRs)

Toll-like receptors (TLRs) mini-review

Mini-review about Toll-like receptors, detailing their role in innate immunity including their expression patterns. 

 

CD45 characterization and isoforms

Toll-like receptors (TLRs) mini-review

Mini-review on the various isoforms of CD45 including their structure and function.

 

Understanding Innate Lymphoid Cells - A Diverse Immune Population

Understanding innate lymphoid cells – a diverse immune population

Mini-review on Innate lymphoid cells covering ILC development, characterization, function and role in disease and immunotherapy.

 

The Mucosal Immune Response in Health and Disease

The structure and regulation of mucosal homeostasis and how this relates to disease and potential immunotherapy.

The structure and regulation of mucosal homeostasis and how this relates to disease and potential immunotherapy.

 

T cell receptor activation, signaling, development and diversity.

The structure and regulation of mucosal homeostasis and how this relates to disease and potential immunotherapy.

Discover the role played  by T cell receptors (TCR) in cell-mediated immune defence.

 

Educational summaries

Easy to follow articles about topics related to our antibodies and immunology.

Immunoglobulins: classes and subclasses

Overview of the five antibody immunoglobulin classes (isotypes).

 

Affinity and avidity of antibodies

Affinity and avidity antibodies

Antigen-antibody interactions, strength measured by affinity and avidity.

Binding affinities chart

Complement system mini-review

A handy binding affinities chart to help determine your antibody purification method.

 

Innate Immunity: TLR2 and TLR4

Innate Immunity: TLR2 and TLR4

Toll-like receptor 2 and 4 (TLR2 and TLR4) structure and expression.

 

TREM-1: Enhancing the innate immune response

TREM-1: Enhancing the Innate Immune response

TREM-1 protein expression and function in innate immunity and the inflammatory response.

 

What is Ebola?

What is Ebola, outbreaks and current research

Article giving an overview of the Ebola virus, recent outbreaks and Ebola research for future outbreak prevention.

 

Dectin-1: Defense against fungal pathogens

Dectin-1: Defense against fungal pathogens

Dectin-1 structure and function.

Application notes

Technical articles written in collaboration with various organizations and partners, highlighting applications of our products.

Cytokines and bovine tuberculosis

Cytokines and bovine Tuberculosis

Methods for cattle TB testing, including the use of cytokines as markers of immune protection.

Harnessing and directing the bovine innate immune system: The importance of TLRs

Harnessing and directing the bovine Innate Immune system: The importance of TLRs

The importance and expression of the toll like receptor (TLR) family in the bovine innate immune system.

Identification of the immunological correlates of protection in ruminants

The Route to identification of the immunological correlates of protection in ruminants

Summary of an Industrial Partnership Award (IPA) project funded by the BBSRC in conjunction with Bio-Rad.

Importance of chicken immunology research and studying host-pathogen interactions

Importance of chicken immunology research and studying host-pathogen interactions

Article describing the importance of researching chicken immune responses.

An Accelerated Approach to Sensitive ADA Assays

Article: An Accelerated Approach to Sensitive ADA Assays

A faster route to selection of high-affinity recombinant antibodies, allowing development of sensitive assays for the monitoring of drug antibodies.

Effective tools for drug monitoring assays

Effective tools for drug monitoring assays

Article describing how scientists validate recombinant monoclonal antibodies for PK and IR assays.

Monitoring antibody immune responses against biotherapeutic drugs

Monitoring antibody immune responses against biotherapeutic drugs

Article describing the challenges in antibody assay development and the special considerations required for monoclonal antibody drugs.

Recombinant antibodies as standards for immunodiagnostic assays

Recombinant Antibodies as Standards for Immunodiagnostic Assays

A method for development of standardization material for autoimmune assays measuring human autoantibodies.

High-Affinity Antibodies for Peptide Enrichment Immuno-MRM

High-Affinity Antibodies for Peptide Enrichment Immuno-MRM

A study showing how recombinant antibodies against short peptides are generated for MS-based assays.

Biomarker Assay Development using Highly Specific Recombinant Antibodies

Development of an assay to discriminate between native and truncated CXCL10 chemokine using custom HuCAL® antibodies

Development of an assay to discriminate between native and truncated CXCL10 chemokine using custom HuCAL® antibodies.

Isolation of Enzyme Active Site-Specific Recombinant Antibodies

Isolation of Enzyme Active Site-Specific Recombinant Antibodies

Generation of antibodies to enzyme active site enabling inhibition experiments and structural studies



alamarBlue® is manufactured for Bio-Rad by Trek Diagnostic Systems U.S.Patent Number 5,501,959. alamarBlue® is a registered trademark of Trek Diagnostic Systems, Inc.