Application Specific Antibodies and Reagents for Immunological Research

Innate immunity is the front line, non-specific and immediate response to pathogens and to the unrecognized self. As a part of the larger immune system, innate immunity comprises a variety of molecules, cell types and signaling cascades which typically do not adapt to previous infection or vaccination.

The innate immune system mediates its response to infection by several means including: direct pathogen destruction, identification and clearance of foreign substances, recruitment of immune mediators by biochemical signaling and stimulation of the adaptive immune response.

Bio-Rad provides an extensive collection of antibodies, reagents, controls and standards for innate immunity research.



Innate Immunity Range 

Macrophage, Monocyte and Dendritic Cell Markers

Range of macrophage, monocyte & dendritic cell markers against target species including human, mouse and rat

NK Cells and Receptors

Antibodies to key traditional markers such as CD16 and CD56 in humans, and CD161 in the mouse plus more recently discovered markers for signaling and effector molecules

Complement

Continually developing range of antibodies and recombinant proteins covering pivotal components of the complement cascade

Pattern Recognition Receptors (PRR)

Wide variety of antibodies to the main types of PRRs; Toll-like receptors (TLR), C-type lectin receptors (CLR), RIG-I-like receptors (RLR) and NOD-like receptors (NLR)

Toll-like Receptors (TLR)

Range of antibodies to mouse and human TLRs including those involved in the TLR signaling cascade & TLRs expressed on adaptive immune cells such as B cells

Cytokines and Chemokines

Range of antibodies and recombinant proteins to cytokines and chemokines, and their associated receptors

Granulocytes

Functional review, markers and antibodies to the four types of granulocyte; basophils, eosinophils, neutrophils and mast cells

Innate Lymphoid Cells (ILC)

ILC development, function and subset characterization of ILC1, ILC2 and ILC3; including key ILC markers and antibodies

Mucosal Immunology

Role and interplay between commensal microbiota, microvillus and resident immune cells.

The Lab Rat

  • Rat facts
  • Immune cell frequencies
  • Lineage specific rat markers
  • Key rat markers and antibodies


Antibody Performance Guarantee

 

Antibody Performance Guarantee

Bio-Rad offers a performance guarantee in key immunological applications including Flow Cytometry, Immunohistochemistry, Immunoassays, Western Blotting and Immunofluorescence.



Highly Cited Extensive Range

Our Innate Immunity portfolio incorporates 4000 products spread across antibodies, kits, reagents, standards and controls. Highly trusted by researchers, our Innate Immunity antibody range primarily covers human, mouse and rat and is highly cited:

  • With over 11,000 references listed on our website
  • F4/80 clone CI:A3-1 has over 900 citations on CiteAb 1
  • CD68 (4 different clones) has over 700 citations on CiteAb 2
     


Useful Innate Immunity Resources

Useful Innate Immunity Resources

To help you obtain publication quality data we have detailed information on how to best control your experiments, including:
 

  • Application guides - for in-depth knowledge about a certain application
  • Detailed information on how to best control your experiments - to help you obtain publication quality data
  • Easy-to-follow application protocols
  • Hands - on tips and tricks to help you improve and optimize your experiments - useful information for both experts and novices


All your Flow Needs Covered

All your Flow Needs Covered

Bio-Rad has over 1,000 flow validated primary conjugated antibodies in immunology, cancer, neuroscience, and regulated cell death.
 

Bio-Rad offers:

  • Label options to build comprehensive multicolor panels; including the StarBright Dyes that have been developed specifically for flow cytometry to give you exceptional brightness with specific excitation and emission profiles
  • Human, mouse and rat are the primary species covered in the range
  • 18 target species for veterinary research
  • Essential FC controls (incl. viability dyes, isotype controls, and Fc blocks)
  • Flow validated supporting reagents, ensuring reproducible data
  • Conjugation kits and secondary antibodies, when primary conjugation is not available


Our range is supported by multiple resources and online tools to help you design your experiments so you can achieve more in the lab.