Application Specific Antibodies and Reagents for Immunological Research
Innate immunity is the front line, non-specific and immediate response to pathogens and to the unrecognized self. As a part of the larger immune system, innate immunity comprises a variety of molecules, cell types and signaling cascades which typically do not adapt to previous infection or vaccination.
The innate immune system mediates its response to infection by several means including: direct pathogen destruction, identification and clearance of foreign substances, recruitment of immune mediators by biochemical signaling and stimulation of the adaptive immune response.
Bio-Rad provides an extensive collection of antibodies, reagents, controls and standards for innate immunity research.
Innate Immunity Range
Range of macrophage, monocyte & dendritic cell markers against target species including human, mouse and rat
Antibodies to key traditional markers such as CD16 and CD56 in humans, and CD161 in the mouse plus more recently discovered markers for signaling and effector molecules
Continually developing range of antibodies and recombinant proteins covering pivotal components of the complement cascade
Wide variety of antibodies to the main types of PRRs; Toll-like receptors (TLR), C-type lectin receptors (CLR), RIG-I-like receptors (RLR) and NOD-like receptors (NLR)
Range of antibodies to mouse and human TLRs including those involved in the TLR signaling cascade & TLRs expressed on adaptive immune cells such as B cells
Range of antibodies and recombinant proteins to cytokines and chemokines, and their associated receptors
Functional review, markers and antibodies to the four types of granulocyte; basophils, eosinophils, neutrophils and mast cells
ILC development, function and subset characterization of ILC1, ILC2 and ILC3; including key ILC markers and antibodies
Role and interplay between commensal microbiota, microvillus and resident immune cells.
Immune cell frequencies
Lineage specific rat markers
Key rat markers and antibodies
Highly Cited Extensive Range
Our Innate Immunity portfolio incorporates 4000 products spread across antibodies, kits, reagents, standards and controls. Highly trusted by researchers, our Innate Immunity antibody range primarily covers human, mouse and rat and is highly cited:
With over 11,000 references listed on our website
F4/80 clone CI:A3-1 has over 900 citations on CiteAb 1
CD68 (4 different clones) has over 700 citations on CiteAb 2
Useful Innate Immunity Resources
To help you obtain publication quality data we have detailed information on how to best control your experiments, including:
Application guides - for in-depth knowledge about a certain application
Detailed information on how to best control your experiments - to help you obtain publication quality data
Easy-to-follow application protocols
Hands - on tips and tricks to help you improve and optimize your experiments - useful information for both experts and novices
All your Flow Needs Covered
Bio-Rad has over 1,000 flow validated primary conjugated antibodies in immunology, cancer, neuroscience, and regulated cell death.
Label options to build comprehensive multicolor panels; including the StarBright Dyes that have been developed specifically for flow cytometry to give you exceptional brightness with specific excitation and emission profiles
Human, mouse and rat are the primary species covered in the range
18 target species for veterinary research
Essential FC controls (incl. viability dyes, isotype controls, and Fc blocks)
Flow validated supporting reagents, ensuring reproducible data
Conjugation kits and secondary antibodies, when primary conjugation is not available
Our range is supported by multiple resources and online tools to help you design your experiments so you can achieve more in the lab.