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Protocol: PK Bridging ELISA for Use with Anti-Dupilumab Antibodies
Pharmacokinetic (PK) Bridging ELISA: for use with anti-dupilumab monoclonal antibody products TZA014 and TZA015
This method provides a procedure for carrying out a PK ELISA with Anti-Dupilumab Antibodies, TZA014 (capture antibody) and HRP-coupled TZA015 (detection antibody), and using dupilumab for the standard curve. The method should always be used in conjunction with product and batch specific information provided with each vial (see product datasheets). This protocol will need to be adjusted for use with different detection methods and immunoassay technology platforms.