Poster: Drug-Target-Complex Specific Antibodies for Pharmacokinetic Analysis of Biotherapeutics
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Monoclonal Generation
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Custom Recombinant Monoclonal Antibody Generation
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Webinars, Videos and Technical Articles
- Webinar: Overcome the Challenges of PK Assay Development Using TrailBlazer Antibodies
- Webinar: Generation of SARS-CoV-2 antibodies in multiple formats within four weeks
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- Webinar: Transform bioanalytical assays with TrailBlazer Antibodies
- Webinar: Control your critical antibody reagents and avoid assay failure
- Webinar: Improve your antibody drug development assays
- Webinar: Optimize your assays using recombinant antibodies selected for desired affinity
- Webinar: The making of recombinant anti-idiotypic antibodies for high performance in bioanalytical assays
- Webinar: Human recombinant antibodies as positive controls and calibrators
- Webinar: How to overcome assay challenges using custom recombinant antibodies
- Webinar: Generation of high affinity recombinant antibodies for application in immuno-MRM
- Video: Generating anti-idiotypic antibodies for bioanalytical assays
- Video: Best practices for characterization and QC of anti-idiotypic antibodies for bioanalysis
- Video: Generation of drug-target complex specific antibodies
- Video: Antibodies for CAR-T cell therapy development
- Article: Monitoring antibody immune responses against biotherapeutic drugs
- Article: Effective tools for drug monitoring assays
- Article: An accelerated approach to sensitive ADA assays
- Article: Isolation of enzyme active site-specific recombinant antibodies by guided selection
- Article: Biomarker Assay Development using Highly Specific Recombinant Antibodies
- Article: Recombinant antibodies as standards for immunodiagnostic assays
- Article: High affinity antibodies for peptide enrichment immuno-MRM
- Article: Generation of antibodies against self-antigens
- Article: Generation and characterization of drug-target complex-specific antibodies
- Article: Antibodies for CAR-T Cell Therapy Development
- Poster: Faster Generation of Anti-Drug Antibodies Using SpyTag Technology
- Poster: CAR T cell analysis with modular antibodies
- Poster: Drug-Target-Complex Specific Antibodies for Pharmacokinetic Analysis of Biotherapeutics
- Poster: Characterization of anti-idiotypic antibodies for high performance in bioanalytical assays
- Poster: Recombinant anti-idiotypic antibodies for antibody drug development
- Poster: Generation of recombinant antibodies for Bio-Plex assays
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Webinars, Videos and Technical Articles
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Custom Recombinant Monoclonal Antibody Generation
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This poster demonstrates how Bio-Rad generates antibodies that recognize monoclonal antibody drugs when bound to their target, using the HuCAL PLATINUM® library and in vitro guided selection. We have named such specificities Type 3, to distinguish them from the anti-idiotypic antibodies that either specifically detect free antibody drug (Type 1) or total drug (Type 2).
We describe the generation and characterization of such reagents for the development of drug monitoring assays, and show how these Type 3 antibodies can be used to develop very specific and sensitive assays that avoid the bridging ELISA format.
Read more about using HuCAL technology to generate antibodies to biosimilars and novel biotherapeutics for the development of bioanalytical assays.
