How to improve your antibody drug development assays with anti-idiotypic antibodies


Human Recombinant Antibodies as Positive Controls and Calibrators

Control and calibrator materials are critical components for many diagnostic immunoassays.

Have you encountered difficulties using patient sera to standardize assays, such as obtaining it in sufficient quantity, free of viruses or other harmful substances and ensuring a consistent long-term supply?

Additionally, the polyclonal nature of human sera means that it contains several different antibodies with a range of affinities, causing variation between different production batches. The lack of consistency of this assay component complicates comparison of assay methods, kit batches and manufacturers.

Fully human, recombinant monoclonal antibodies with desired specificity and tailored isotype provide the answer.

Watch our webinar to find out how we use the HuCAL® antibody library and phage display technology to generate custom recombinant antibodies as alternatives to human sera, with the following advantages:

  • Fully human, defined and pure reagents
  • Unlimited supply, easy to produce in large quantities
  • Stable, long shelf life
  • Preparations do not contain harmful substances
  • Monospecific, known affinities, known epitopes
  • Defined isotypes (IgG, IgM, IgA, IgE)
  • Sequence available, security and production flexibility

Human Recombinant Antibodies as Positive Controls and Calibrators

Speaker: Achim Knappik Ph.D. Group R&D Manager, Bio-Rad AbD Serotec GmbH

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To discuss a custom HuCAL antibody generation project, contact


Tel: +49 89 80 90 95 45

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