How to improve your antibody drug development assays with anti-idiotypic antibodies


How to improve your antibody drug development assays with anti-idiotypic antibodies

  • Do you need to develop highly sensitive PK and ADA assays?
  • Did you know that three different types of anti-drug antibody can be generated to bind specifically in different ways to your candidate monoclonal antibody drug?

These highly specialized antibodies can be used to set up pharmacokinetic (PK) assays in different formats to measure free or total drug levels in preclinical and clinical samples, or as positive controls in anti-drug antibody (ADA) assays.

Listen to our recorded webinar to find out how recombinant monoclonal anti-idiotypic antibodies are generated at Bio-Rad, and how they can be used to develop highly specific and sensitive PK and ADA assays.

The presentation covers how we use HuCAL® technology to overcome the limitations of traditional antibody generation methods, resulting in the fast development of fully human Fab and full immunoglobulin anti-idiotypic antibodies.

Data is presented to show development of antibodies binding specifically and with high affinity to well-known drugs, such as adalimumab, trastuzumab and cetuximab, plus we explain our unique capability for developing antibodies against drug-target complexes.

Webinar Recording

Are HuCAL® anti-idiotypic antibodies part of your solution?

Speaker: Dr Christian Frisch, R&D Manager, Bio-Rad.

For technical and applications support contact

North America


Toll Free: +1 800 265 7376

Tel: +1 919 878 7978



Tel: +49 89 80 90 95 21

UK & Worldwide


Tel: +44 1865 852 700

To discuss a custom HuCAL antibody generation project, contact


Tel: +49 89 80 90 95 45

Or complete our online inquiry form

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