Recombinant Anti-Idiotypic Antibodies for Antibody Drug Development

Presented at PEGS Europe, Lisbon 3-7 November 2014 and at Antibody Engineering and Therapeutics, Huntington Beach 7-11 December 2014

This poster illustrates the suitability of HuCAL® recombinant custom monoclonal antibodies for Pharmacokinetic (PK) assays and Immune Reponse (IR) assays and includes

  • Summary of the anti-idiotypic (anti-ID) antibody generation process
  • Example of PK assay for quantification
  • Example of IR assay, with anti-ID antibody mimicking anti-drug antibody (ADA) response
  • Anti-biotherapeutic antibody binding modes and properties
  • List of ready-made antibodies available

Read more about using HuCAL technology to generate antibodies to biosimilars and novel biotherapeutics

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