Neural stem cells (NSCs) were first isolated in mice and subsequently in higher organisms comprising non-human primates and humans. They are present in both embryos and adults. The two areas of the adult brain that display neural proliferation are the dentate gyrus and the subventricular zone. Neural stem cells self renew and differentiate into neurons, astrocytes, and oligodendrocytes. However, they have also been shown to contribute to hematopoiesis following their injection into irradiated mice.
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