CD34 is a monomeric single-pass type I membrane protein. CD34 is selectively expressed on hematopoietic stem cells, endothelial cells, leukemic blast cells, and normal hematopoietic progenitors. The antibodies against CD34 are grouped into three classes based on the resistance of the cognate epitope to enzymatic cleavage by neuraminidase, chymopapain, and a glycoprotease from Pasteurella haemolytica.
Epitopes recognized by class I antibodies are sensitive to all the three proteases. Class II (QBEND/10) are resistant to neuroaminidase, while class III (clone 581) are resistant to neuraminidase, chymopapain and glycoprotease.
|Description||Specificity||Target||Format||Host||Isotype||Clone||Applications||Citations||Product Type||Code||Validation Types|
Mouse anti Human Class II antibody clone QBEND/10
Mouse anti Human CD34 Class III clone 581
Rat anti Mouse CD34 clone MEC14.7
Mouse anti Dog CD34 clone 1H6 PE conjugated