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Hematopoietic stem cells (HSCs) are tissue-specific, multipotent stem cells that give rise to all blood cells. They reside in the bone marrow in a low oxygen environment called the “niche”, where they remain quiescent before eventually dividing and differentiating.
B and T lymphocytes, natural killer cells, dendritic cells, monocytes, platelets, and erythrocytes all originate from hematopoietic stem cells through lineage-specific intermediate progenitors. Hematopoietic stem cells have been extensively used in therapy for certain blood disorders and cancers, and are approved for treatment in humans.
HSCs are a rare cell population, with only around 1 in 2,000 to 1 in 10,000 bone marrow cells HSCs. Popular markers to identify this cell type include: Sca-1, CD27, CD34, CD38, CD43, CD48, CD117, CD150 and aldehyde dehydrogenase-1.
Bio-Rad provides a broad collection of HSCs antibodies. Click on the related links below to explore our product range by marker or use the filters in the table below to sort the attributes in order to find the antibody that fits your exact requirements.