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Stem cells are subjected to many processes and fates. They can self-renew in symmetrical or asymmetrical divisions, become quiescent, differentiate, leave the niche, or even die by apoptosis.
All of these processes are tightly controlled by internal and external signals to ensure expansion or maintenance of the stem cell pool and supply of newborn stem cells.
A number of signaling pathways including Notch, Wnt, MAPK, Akt and SMAD pathways have been shown to be involved in regulating stem cell fate.
Staining of formalin fixed, paraffin embedded human cerebellum with Rabbit Anti-Human WNT28 (AHP1136).
Manipulation of signaling pathways is also critical in reprograming cells to form induced pluripotent stem cells.
Bio-Rad provides a broad collection of stem cell antibodies guaranteed for use in key applications such as flow cytometry and western blotting. Click on the related links below to explore our product range by marker or use the filters in the table below to sort the attributes in order to find the antibody that fits your exact requirements.