Stem cells are subjected to many processes and fates. For instance, they can self renew in symmetrical or asymmetrical divisions, become quiescent, differentiate, leave the niche, and even die by apoptosis. All these processes are tightly controlled by internal and external signals to ensure expansion or maintenance of the stem cell pool and supply of newborn cells. Notch, Wnt and SMAD pathways have been shown to be involved however their interaction, particularly in vivo in the niche, is not fully understood.
Bio-Rad offers many performance guaranteed antibodies suitable for studying stem cell signaling pathways which you can view below.
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