CD4 antibody | OX-68
Mouse anti Rat CD4 (Domains 3 and 4)
- Product Type
- Monoclonal Antibody
- Clone
- OX-68
- Isotype
- IgG2a
- Specificity
- CD4
- Region
- (DOMAINS 3 AND 4)
Mouse anti Rat CD4 (Domains 3 and 4) monoclonal antibody, clone OX-68 recognizes domains 3 and 4 of rat CD4, a single pass type I membrane glycoprotein. |
- Target Species
- Rat
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% sodium azide (NaN3)
- Carrier Free
- Yes
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunized BALB/c mice were fused with cells of the NS1 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry | 1/50 | 1/100 |
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells in 100μl.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Mouse IgG2a Negative Control | MCA1210 | F | 100 Tests | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Mouse IgG2a Negative Control |
References for CD4 antibody
-
Kerr, J.S, and Wright, G.J. (2012) Avidity-based extracellular interaction screening (AVEXIS) for the scalable detection of low-affinity extracellular receptor-ligand interactions.
J Vis Exp. 5(61): e3881. -
Crosnier, C. et al. (2013) A library of functional recombinant cell-surface and secreted P. falciparum merozoite proteins.
Mol Cell Proteomics. 12 (12): 3976-86. -
van Wilgenburg, B. et al. (2014) The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4.
PLoS One. 9 (1): e86071. -
Crosnier, C. et al. (2016) Binding of Plasmodium falciparum Merozoite Surface Proteins DBLMSP and DBLMSP2 to Human Immunoglobulin M Is Conserved among Broadly Diverged Sequence Variants.
J Biol Chem. 291 (27): 14285-99. -
Liu, Y. et al. (2018) Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.
Neuron. 97 (6): 1261-1267.e4. -
Proto, W.R. et al. (2019) Adaptation of Plasmodium falciparum. to humans involved the loss of an ape-specific erythrocyte invasion ligand.
Nat Commun. 10 (1): 4512. -
Sharma, S. & Wright, G.J. (2020) Cell Surface Receptor Identification Using Genome-Scale CRISPR/Cas9 Genetic Screens.
J Vis Exp. 2020 Jun 06 (160). -
Crosnier, C. et al. (2022) Screening of a Library of Recombinant Schistosoma mansoni Proteins With Sera From Murine and Human Controlled Infections Identifies Early Serological Markers.
J Infect Dis. 225 (8): 1435-46.
View The Latest Product References
- RRID
- AB_567282
- UniProt
- P05540
- Entrez Gene
- Cd4
- GO Terms
- GO:0007155 cell adhesion
- GO:0016021 integral to membrane
- GO:0006955 immune response
- GO:0019901 protein kinase binding
- GO:0045058 T cell selection
MCA1022R
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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