IgGb antibody | CVS39
Mouse anti Horse IgGb antibody, clone CVS39 (MCA1901GA) used to evaluate IgGb levels in horse sera by ELISA
Image caption:
IgGb titers between the non-surviving and surviving groups. Values are expressed as ELISA units. Asterisks indicate statistically significant differences (p <0.05). NS, not significant.
From: Mizuguchi, Y.; Tsuzuki, N.; Ebana, M.D.; Suzuki, Y.; Kakuda, T.
IgG Subtype Response against Virulence-Associated Protein A in Foals Naturally Infected with Rhodococcus equi.
Vet. Sci. 2024, 11, 422.
doi: 0.3390/vetsci11090422
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Mouse anti Horse IgGb antibody, clone CVS39 (MCA1901GA) used to evaluate IgGa levels in horse sera by ELISA
Image caption:
Correlation between serum levels of IgG subtypes in the non-surviving and surviving groups. The regression line (blue dots) and multiple correlation coefficient (R) are indicated. Results of tests of no correlation are expressed as p-values. Red dots indicate the regression line of the non-surviving group for each IgG subtype.
From: Mizuguchi, Y.; Tsuzuki, N.; Ebana, M.D.; Suzuki, Y.; Kakuda, T.
IgG Subtype Response against Virulence-Associated Protein A in Foals Naturally Infected with Rhodococcus equi.
Vet. Sci. 2024, 11, 422.
doi: 0.3390/vetsci11090422
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Mouse anti Horse IgGb antibody, clone CVS39 (MCA1901GA) used to evaluate IgGa levels in horse sera by ELISA
Image caption:
Correlation between serum levels of IgG subtypes in the non-surviving and surviving groups. The regression line (blue dots) and multiple correlation coefficient (R) are indicated. Results of tests of no correlation are expressed as p-values. Red dots indicate the regression line of the non-surviving group for each IgG subtype.
From: Mizuguchi, Y.; Tsuzuki, N.; Ebana, M.D.; Suzuki, Y.; Kakuda, T.
IgG Subtype Response against Virulence-Associated Protein A in Foals Naturally Infected with Rhodococcus equi.
Vet. Sci. 2024, 11, 422.
doi: 0.3390/vetsci11090422
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Filter by Application:
E ResetMouse anti Horse IgGb
- Product Type
- Monoclonal Antibody
- Clone
- CVS39
- Isotype
- IgG1
- Specificity
- IgGb
Antibody Quality and Performance Guarantee
| Mouse anti Horse IgGb antibody, clone CVS39 recognizes equine IgGb, also known as equine IgG4/7 (Keggan et al. 2013), and shows no significant binding to other IgG subclasses. Equine IgGb is an immunologlobulin with a molecular weight (MW) of approximately 160kDa, the MW of the light chain being 27kDa, common to all equine IgG subclasses, while the heavy chain has a MW of 53kDa, specific to IgGb (Sheoran et al. 1998). Equine IgGb has been demonstrated to be involved in long lasting immunity following respiratory-related viral infections such as Equine Herpes virus Type 4 (EHV-4) (Mizukoshi et al. 2002) and Equine Influenza (Soboll et al. 2003). In addition to Mouse anti Horse IgGb, clone CVS39, Bio-Rad also offer a range of other monoclonal and polyclonal antibodies that are specific to equine immunoglobulin classes and subclasses. |
- Target Species
- Horse
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% sodium azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Purified equine IgGb.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised Balb/c mice were fused with cells of the mouse X63-Ag8.653 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1/5000 | 1/50000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Purified Horse IgG | PEP001 | E ID | 10 mg |
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| List Price | Your Price | ||||||
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| Description | Purified Horse IgG | ||||||
References for IgGb antibody
-
Sheoran, A.S. et al. (1998) Monoclonal antibodies to subclass-specific antigenic determinants on equine immunoglobulin gamma chains and their characterization.
Vet Immunol Immunopathol. 62 (2): 153-65. -
Lewis, M.J. et al. (2008) The different effector function capabilities of the seven equine IgG subclasses have implications for vaccine strategies.
Mol Immunol. 45 (3): 818-27. -
Keggan, A. et al (2013) Production of seven monoclonal equine immunoglobulins isotyped by multiplex analysis
Vet Immunol Immunopathol.153(3-4):187-93 -
Palm, A.E. et al. (2016) Secretory immunoglobulin A and immunoglobulin G in horse saliva.
Vet Immunol Immunopathol. 180: 59-65. -
Mizuguchi, Y. et al. (2024) IgG Subtype Response against Virulence-Associated Protein A in Foals Naturally Infected with Rhodococcus equi
Veterinary Sciences. 11 (9): 422.
Further Reading
-
Mizukoski, F. et al (2002) IgG antibody subclass response against equine herpesvirus type 4 in horses.
Vet Immunol Immunopathol. 88(1-2):97-101. -
Soboll, G. et al (2003) Regional antibody and cellular immune responses to equine influenza virus infection, and particle mediated DNA vaccination.
Vet Immunol Immunopathol. 94(1-2):47-62.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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