Cdk4 antibody | DCS-31.2

Mouse anti CDK4

Product Type
Monoclonal Antibody
Clone
DCS-31.2
Isotype
IgG1
Format
Purified
Specificity
Cdk4

Product Code Applications Pack Size List Price Your Price Qty
MCA1994
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
C IP WB 0.1 mg loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Mouse anti CDK4 antibody clone DCS31.2 recognizes cyclin dependent kinase 4 (Cdk4), a ~34 kDa protein involved in the regulation of cell cycle progression between G1 and S.

Mouse anti CDK4 antibody clone DCS31.2 does not cross react with other cdk's and does not co-precipitate the D type cyclins bound to cdk4.
PrecisionAb Antibodies

Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Human
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Antibody purified from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.08% sodium azide (NaN3)
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
Guaranteed for 12 months from the date of despatch or until the date of expiry, whichever comes first. Please see label for expiry date.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Frozen
Immunoprecipitation
Western Blotting
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

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References for Cdk4 antibody

  1. Elledge, S.J. (1996) Cell cycle checkpoints: preventing an identity crisis.
    Science. 274 (5293): 1664-72.

RRID
AB_2260415
UniProt
P11802
Entrez Gene
CDK4
GO Terms
GO:0000080 G1 phase of mitotic cell cycle
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000084 S phase of mitotic cell cycle
GO:0005515 protein binding
GO:0000307 cyclin-dependent protein kinase holoenzyme complex
GO:0005829 cytosol
GO:0004693 cyclin-dependent protein kinase activity
GO:0005524 ATP binding
GO:0006468 protein phosphorylation
GO:0042493 response to drug
GO:0010468 regulation of gene expression
GO:0048146 positive regulation of fibroblast proliferation
GO:0051301 cell division
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"