Cdk4 antibody | DCS-31.2
KO Validated
Mouse anti CDK4 antibody clone DCS31.2 recognizes cyclin dependent kinase 4 (Cdk4), a ~34 kDa protein involved in the regulation of cell cycle progression between G1 and S.
Mouse anti CDK4 antibody clone DCS31.2 does not cross react with other cdk's and does not co-precipitate the D type cyclins bound to cdk4.
Mouse anti CDK4 antibody clone DCS31.2 does not cross react with other cdk's and does not co-precipitate the D type cyclins bound to cdk4.
Product Details
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Human Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.08% Sodium Azide - Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. - Guarantee
- Guaranteed until date of expiry. Please see product label.
More Information
- UniProt
- P11802
- Entrez Gene
- CDK4
- GO Terms
- GO:0000080 G1 phase of mitotic cell cycle
- GO:0000082 G1/S transition of mitotic cell cycle
- GO:0000084 S phase of mitotic cell cycle
- GO:0005515 protein binding
- GO:0000307 cyclin-dependent protein kinase holoenzyme complex
- GO:0005829 cytosol
- GO:0004693 cyclin-dependent protein kinase activity
- GO:0005524 ATP binding
- GO:0006468 protein phosphorylation
- GO:0042493 response to drug
- GO:0010468 regulation of gene expression
- GO:0048146 positive regulation of fibroblast proliferation
- GO:0051301 cell division
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of Cdk4 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Frozen | |||
| Immunoprecipitation | |||
| Western Blotting |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
Product Specific References
References for Cdk4 antibody
-
Elledge, S.J. (1996) Cell cycle checkpoints: preventing an identity crisis.
Science. 274 (5293): 1664-72.
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