TCF7 antibody

Rabbit anti Human TCF7

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
TCF7

Product Code Applications Pack Size List Price Your Price Qty
AHP3108
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 0.1 ml loader
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loader
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Rabbit anti Human TCF7 antibody recognizes transcription factor 7.

TCF7 is a transcription factor involved in the regulation of the expression of several genes located in the cells of the liver (Courtois et al. 1987). TCF7 has been shown to promote proliferation in glioblastoma multiforme cells through upregulation of c-Myc and acts as an unfavorable prognostic marker of glioblastoma multiforme (Su et al. 2018).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human TCF7 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the N-terminal region of human TCF7
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
P36402
Entrez Gene
TCF7
GO Terms
GO:0005515 protein binding
GO:0003702 RNA polymerase II transcription factor activity
GO:0016055 Wnt receptor signaling pathway
GO:0005634 nucleus
GO:0006350 transcription
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006955 immune response
GO:0010843 promoter binding
GO:0071353 cellular response to interleukin-4
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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