Mouse anti Canine distemper virus antibody, clone 7515 recognizes the envelope protein of canine distemper virus (CDV), a negatively stranded RNA morbillivirus. CDV infection induces a systemic, often fatal disease in a broad and expanding host spectrum among the Carnivora. CDV is highly contagious, and transmission occurs predominantly via aerosols, resulting in neuroinvasiveness and severe immunosuppression. Mortality rates during CDV outbreaks can exceed 80%.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Envelope protein of canine distemper virus.
- Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Canine Distemper Virus antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
Product Specific References
References for Canine Distemper Virus antibody
Kabak YB et al. (2015) Immunohistochemical detection of autophagy-related microtubule-associated protein 1 light chain 3 (LC3) in the cerebellums of dogs naturally infected with canine distemper virus.
Biotech Histochem. Jul 16. [Epub ahead of print]
Yarim, M. et al. (2011) Ki67 expression in the cerebellum of dogs with distemper
Revue de Médecine Vétérinaire 162: 246-51.
Harder, T.C. and Osterhaus, A.D. (1997) Canine distemper virus--a morbillivirus in search of new hosts?
Trends Microbiol. 5: 120-124.