CD45 antibody | VPM18



Filter by Application:
F C ResetMouse anti Sheep CD45
- Product Type
- Monoclonal Antibody
- Clone
- VPM18
- Isotype
- IgG1
- Specificity
- CD45
Mouse anti Sheep CD45, clone VPM18 recognizes the ovine homologue of human CD45 otherwise known as LCA (leucocyte common antigen), a type I transmembrane glycoprotein and member of the protein-tyrosine phosphatase (PTP) family, expressed at high levels on all nucleated cells of haematopoietic origin, and which exists in several isoforms generated by the alternative splicing. CD45 is a signal transduction protein vital for T and B cell antigen receptor-mediated activation, and is involved in many aspects of cellular processes, including growth, differentiation and oncogenic transformation. CD45 associates with many cell surface antigens, including CD2, CD3, CD4, CD26 and CD90. Mouse anti Sheep CD45, clone VPM18 recognizes all isoforms of the ovine CD45 molecule. |
- Target Species
- Sheep
- Species Cross-Reactivity
-
Target Species Cross Reactivity Human Bovine - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Sheep T lymphocytes.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS0 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry | ![]() |
1/25 | 1/200 |
Immunohistology - Frozen | ![]() |
||
Immunoprecipitation | ![]() |
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Mouse anti Sheep CD45R | MCA2221GA | F | 0.1 mg |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Mouse anti Sheep CD45R | ||||||
Mouse anti Sheep CD45R:RPE | MCA2221PE | F | 100 Tests |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Mouse anti Sheep CD45R:RPE | ||||||
Mouse anti Bovine CD14:FITC | MCA2678F | F | 0.1 mg |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Mouse anti Bovine CD14:FITC | ||||||
Mouse anti Bovine CD14 | MCA2678GA | F IF | 0.1 mg |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Mouse anti Bovine CD14 |
References for CD45 antibody
-
Hopkins, J. & Dutia, B.M. (1990) Monoclonal antibodies to the sheep analogues of human CD45 (leucocyte common antigen), MHC class I and CD5. Differential expression after lymphocyte activation in vivo.
Vet Immunol Immunopathol. 24 (4): 331-46. -
Pastoret P-P., et. al. (1998) Immunology of cattle (in Handbook of Veterbrate Immunology)
Chapter XIII, p445
- Synonyms
- LCA
- RRID
- AB_1220450
MCA896GA


If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Sheep ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up