SWC5 antibody | b37c10
Mouse anti Pig SWC5
- Product Type
- Monoclonal Antibody
- Clone
- b37c10
- Isotype
- IgG1
- Specificity
- SWC5
Antibody Quality and Performance Guarantee
| Mouse anti Pig SWC5 antibody, clone b37c10 recognizes the porcine SWC5 cell surface antigen. SWC5 has a molecular weight of 180 kDa and is expressed only on subset of γ/δ T cells. SWC5 and CD2 expression divides γδ T cells into three subpopulations: CD2-SWC5-, CD2-SWC5+ and CD2+SWC5- γδ T cells subsets. The vast majority of CD2-SWC5- and CD2-SWC5+ T cells are negative for CD8α and SLA-DR and positive for CD27. Only thymus and spleen has an extra CD2+SWC5+ population. |
- Target Species
- Pig
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Porcine T cells
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
1/10 | 1/200 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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| List Price | Your Price | ||||||
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| Description | Mouse IgG1 Negative Control | ||||||
References for SWC5 antibody
-
Sedlak, C. et al. (2014) CD2 and CD8α define porcine γδ T cells with distinct cytokine production profiles.
Dev Comp Immunol. 45 (1): 97-106. -
Schilloks, M.C. et al. (2023) Effects of GHR Deficiency and Juvenile Hypoglycemia on Immune Cells of a Porcine Model for Laron Syndrome.
Biomolecules. 13 (4)Mar 26 [Epub ahead of print]. -
Giese, I.M. et al. (2020) Chronic Hyperglycemia Drives Functional Impairment of Lymphocytes in Diabetic INS(C94Y) Transgenic Pigs.
Front Immunol. 11: 607473.
Further Reading
-
Binns, R.M. et al. (1992) Subsets of null and gamma delta T-cell receptor+ T lymphocytes in the blood of young pigs identified by specific monoclonal antibodies.
Immunology. 77 (2): 219-27. -
Binns, R.M. (1994) The Null/gamma delta TCR+ T cell family in the pig.
Vet Immunol Immunopathol. 43 (1-3): 69-77. -
Piriou-guzylack, L. & Salmon, H. (2008) Membrane markers of the immune cells in swine: an update.
Vet Res. 39 (6): 54.
MCA6050GA
1806
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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