CD52 antibody | K263.3D7

Mouse anti Pig CD52
- Product Type
- Monoclonal Antibody
- Clone
- K263.3D7
- Isotype
- IgG1
- Specificity
- CD52
Mouse anti Pig CD52, clone K263.3D7 is a monoclonal antibody recognizing porcine SWC1a, originally assigned at the 1st International Swine Cluster of Differentiation (CD) Workshop. SWC1a (CD52) is a cell surface molecule which is expressed by most leucocytes including resting T cells, monocytes and granulocytes. SWC1a is not expressed by the majority of B cells, erythrocytes or platelets (Leitner et al. 2012). SWC1a, expressed at very much higher levels on monocytes than on mature macrophages, can be used with SWC9, expressed exclusively on mature tissue macrophages, to study intermediate stages of monocyte-macrophage differentiation (Sanchez et al. 1999). |
- Target Species
- Pig
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% sodium azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Pig peripheral blood mononuclear cells
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry | ![]() |
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 1x106 cells in 100μl
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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Description | Mouse IgG1 Negative Control |
References for CD52 antibody
-
Weesendorp, E. et al. (2013) Comparative analysis of immune responses following experimental infection of pigs with European porcine reproductive and respiratory syndrome virus strains of differing virulence.
Vet Microbiol. 163 (1-2): 1-12. -
Saalmüller A et al. (1994) Analysis of mAb reactive with the porcine SWC1.
Vet Immunol Immunopathol. 43 (1-3): 255-8. -
Sorensen, N.S. et al. (2011) Enhancement of muramyldipeptide (MDP) immunostimulatory activity by controlled multimerization on dendrimers.
Macromol Biosci. 11 (11): 1484-90. -
Tsai, Y.C. et al. (2010) Porcine circovirus type 2 (PCV2) induces cell proliferation, fusion, and chemokine expression in swine monocytic cells in vitro.
Vet Res. 41 (5): 60. -
Tsai, Y-C. et al. (2014) Differences in the Expression of Innate Immune Response-Modulating Genes in Blood Monocytes Between Subclinically Porcine Circovirus Type2 (PCV2)-Infected and PCV2-Free Pigs Prior to and After Lipopolysaccharide Stimulation in vitro.
Taiwan Vet J. 1450005 -
Abu-El-Haija, M. et al. (2011) An activated immune and inflammatory response targets the pancreas of newborn pigs with cystic fibrosis.
Pancreatology. 11 (5): 506-15. -
Nielsen, O.L. et al. (2021) A porcine model of subcutaneous Staphylococcus aureus. infection: a pilot study.
APMIS. Mar 01 [Epub ahead of print].
Further Reading
-
Piriou-Guzylack, L. (2008) Membrane markers of the immune cells in swine: an update.
Vet Res. 39: 54. -
McCullough, K.C. et al. (1999) Intermediate stages in monocyte-macrophage differentiation modulate phenotype and susceptibility to virus infection.
Immunology 98 (2): 203-12.
- Synonyms
- SWC1a
MCA2088GA

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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