IgM antibody | 47.2.E9
Mouse anti Human IgM
- Product Type
- Monoclonal Antibody
- Clone
- 47.2.E9
- Isotype
- IgG1
- Specificity
- IgM
- Region
- MU CHAIN
Mouse anti Human IgM antibody, clone 47.2.E9 is a monoclonal antibody raised in mouse that recognises the mu heavy chain of human immunoglobulin M (IgM). This antibody has been validated for ELISA applications. Immunoglobulin M (IgM) is the first antibody isotype produced during the initial stages of a primary immune response in humans and plays a key role in early humoral immunity. It exists both as a membrane-bound receptor on naïve and immature B cells and as a secreted pentameric molecule produced by plasma cells. IgM is widely found in the bloodstream and lymphoid tissues, including the spleen and bone marrow. Through its ability to bind antigens with high avidity, IgM efficiently activates the classical complement pathway, notably via interaction with C1q, and contributes to rapid pathogen neutralisation and clearance. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3) - Carrier Free
- Yes
- Immunogen
- Purified human IgM.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | 1/5000 | 1/10000 |
- RRID
- AB_617312
- UniProt
- P01871
- Entrez Gene
- IGHM
- GO Terms
- GO:0003823 antigen binding
- GO:0016021 integral to membrane
- GO:0005624 membrane fraction
5278-5159
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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