IgG4 antibody | HP6023
Mouse anti Human IgG4
- Product Type
- Monoclonal Antibody
- Clone
- HP6023
- Isotype
- IgG3
- Specificity
- IgG4
Antibody Quality and Performance Guarantee
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Mouse anti Human IgG4 antibody, (clone HP6023) is a monoclonal antibody that recognizes human immunoglobulin G subclass 4 (IgG4). This antibody has been reported to work in the following applications; ELISA, Immunohistology - Frozen. IgG4 is the least abundant human IgG subclass in serum and has been studied in the context of chronic infection and immune mediated disease. Mouse anti Human IgG4 has been used to detect IgG4 antibodies in immunological studies, including investigations of parasitic infection and autoimmune disease. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared from tissue culture supernatant
- Buffer Solution
- Borate buffered saline
- Preservative Stabilisers
- None present
- Immunogen
- Pool of 5-6 individually purified Human IgG4 myeloma proteins
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- Guaranteed for 12 months from the date of despatch or until the date of expiry, whichever comes first. Please see label for expiry date.
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
||
| Immunohistology - Frozen | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
References for IgG4 antibody
-
Mutapi, F. et al. (2002) The effect of treatment on the age-antibody relationship in children infected with Schistosoma mansoni and Schistosoma haematobium.
Mem Inst Oswaldo Cruz. 97 Suppl 1: 173-80. -
Martinsson, K. et al. (2017) Immunoglobulin (Ig)G1 and IgG4 anti-cyclic citrullinated peptide (CCP) associate with shared epitope, whereas IgG2 anti-CCP associates with smoking in patients with recent-onset rheumatoid arthritis (the Swedish TIRA project).
Clin Exp Immunol. 188 (1): 53-62.
- RRID
- AB_2565207
- UniProt
- P01861
- Entrez Gene
- IGHG4
- GO Terms
- GO:0003823 antigen binding
- GO:0005576 extracellular region
- GO:0005624 membrane fraction
- GO:0006955 immune response
View more products with IgG specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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