HLA DR antibody | L243

Mouse anti Human HLA DR

Product Type
Monoclonal Antibody
Clone
L243
Isotype
IgG2a
Specificity
HLA DR

Product Code Applications Pack Size List Price Your Price Qty
MCA2812GA
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
F 0.1 mg loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Mouse anti Human HLA DR antibody, clone L243 recognizes the human HLA DR antigen, a member of the MHC class II family, which is expressed by B cells, activated T cells and monocytes. Mouse anti Human HLA DR antibody, clone L243 binds to a conformational epitope on HLA DRα and does not cross react with HLA DQ and HLA DP.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Chimpanzee
Baboon
Cynomolgus monkey
Rhesus Monkey
Marmoset
African green monkey
Dog
Squirrel monkey
Pig-tailed macaque
Marmoset
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml
Regulatory
For research purposes only
Guarantee
Guaranteed for 12 months from the date of despatch or until the date of expiry, whichever comes first. Please see label for expiry date.

Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry Neat 1/10
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul

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References for HLA DR antibody

  1. Wang, D. et al. (2002) The influence of HLA-DR4 (0401) on the immune response to type II collagen and the development of collagen induced arthritis in mice.
    J Autoimmun. 18 (2): 95-103.
  2. Chaturvedi, C.P. et al. (2018) Altered Expression of Hematopoiesis Regulatory Molecules in Lipopolysaccharide-Induced Bone Marrow Mesenchymal Stem Cells of Patients with Aplastic Anemia.
    Stem Cells Int. 2018: 6901761.
  3. Kim, S.H. et al. (2019) Forkhead box O1 (FOXO1) controls the migratory response of Toll-like receptor (TLR3)-stimulated human mesenchymal stromal cells.
    J Biol Chem. 294 (21): 8424-37.
  4. Temme, S. et al. (2019) Assembly, Intracellular Transport, and Release of MHC Class II Peptide Receptors.
    Methods Mol Biol. 1988: 297-314.
  5. Ngugi, S. et al. (2022) The innate immune response in the marmoset during the acute pneumonic disease caused by Burkholderia pseudomallei.
    Infect Immun. : IAI0055021.
  6. Nelson, M. et al. (2021) Comparison of experimental MERS-CoV infection acquired by three individual routes of infection in the common marmoset.
    J Virol. : JVI0173921.

UniProt
Q29769
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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