CD45RB antibody | MEM-55



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F ResetMouse anti Human CD45RB
- Product Type
- Monoclonal Antibody
- Clone
- MEM-55
- Isotype
- IgG1
- Specificity
- CD45RB
Quick Links:
Mouse anti Human CD45RB antibody, clone MEM-55 recognizes the isoform of the leucocyte common antigen encoded by exon B and stains B cells, most T cells and monocytes. Mouse anti Human CD45RB antibody, clone MEM-55 immunoprecipitates bands of 190, 200 and 205 kDa. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rhesus Monkey Horse Goat Llama Monkey - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide - Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry | ![]() |
1/50 | 1/100 |
Immunohistology - Frozen | ![]() |
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Immunohistology - Paraffin | ![]() |
1/50 | 1/200 |
Immunoprecipitation | ![]() |
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells in 100ul
- Immunohistology
- This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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List Price | Your Price | ||||||
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Description | Mouse IgG1 Negative Control |
References for CD45RB antibody
-
Davis, W.C. et al. (2007) Use of flow cytometry to identify monoclonal antibodies that recognize conserved epitopes on orthologous leukocyte differentiation antigens in goats, llamas, and rabbits.
Vet Immunol Immunopathol. 119: 123-30. -
Ibrahim, S. et al. (2007) Screening of anti-human leukocyte monoclonal antibodies for reactivity with equine leukocytes.
Vet Immunol Immunopathol. 119: 63-80. -
Windhagen, A. et al. (2007) Altered CD45 isoform expression in C77G carriers influences cytokine responsiveness and adhesion properties of T cells.
Clin Exp Immunol. 150: 509-17. -
Blaylock, M.G. et al. (2003) Eosinophils from patients with asthma express higher levels of the pan-leucocyte receptor CD45 and the isoform CD45RO.
Clin Exp Allergy. 33: 936-41. -
Khan, A.A. et al. (2015) Therapeutic Immunization with a Mixture of Herpes Simplex Virus Type 1 Glycoprotein D Derived "Asymptomatic" Human CD8+ T-cell Epitopes Decreases Spontaneous Ocular Shedding in Latently Infected HLA Transgenic Rabbits: Association with Low Frequency of Local PD-1+TIM-3+CD8+ Exhausted T Cells.
J Virol. pii: JVI.00788-15. -
Ponchel, F. et al. (2014) An immunological biomarker to predict MTX response in early RA.
Ann Rheum Dis. 73 (11): 2047-53. -
Hunt, L. et al. (2016) T cell subsets: an immunological biomarker to predict progression to clinical arthritis in ACPA-positive individuals.
Ann Rheum Dis. 75 (10): 1884-9.
- RRID
- AB_321430
- UniProt
- P08575
- Entrez Gene
- PTPRC
- GO Terms
- GO:0001915 negative regulation of T cell mediated cytotoxicity
- GO:0001960 negative regulation of cytokine-mediated signaling pathway
- GO:0002378 immunoglobulin biosynthetic process
- GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
- GO:0005887 integral to plasma membrane
- GO:0005925 focal adhesion
- GO:0006469 negative regulation of protein kinase activity
- GO:0006470 protein dephosphorylation
- GO:0007411 axon guidance
- View More GO Terms
- GO:0019901 protein kinase binding
- GO:0030890 positive regulation of B cell proliferation
- GO:0033261 regulation of S phase
- GO:0042100 B cell proliferation
- GO:0045121 membrane raft
- GO:0050852 T cell receptor signaling pathway
- GO:0050853 B cell receptor signaling pathway
- GO:0050857 positive regulation of antigen receptor-mediated signaling pathway
- GO:0051209 release of sequestered calcium ion into cytosol
- GO:0051607 defense response to virus
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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