Calcitonin Receptor antibody | 31/01-1H10-4-1-14



Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rabbit - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide - Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P30988
- Entrez Gene
- CALCR
- GO Terms
- GO:0005515 protein binding
- GO:0004948 calcitonin receptor activity
- GO:0005887 integral to plasma membrane
- GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway
- GO:0007204 elevation of cytosolic calcium ion concentration
- GO:0032841 calcitonin binding
- GO:0045762 positive regulation of adenylate cyclase activity
- GO:0051384 response to glucocorticoid stimulus
- Regulatory
- For research purposes only
Applications of Calcitonin Receptor antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | 1/1000 | 1/5000 | |
Flow Cytometry | |||
Immunofluorescence | |||
Immunohistology - Frozen | |||
Immunohistology - Paraffin 1 | 1/50 | 1/500 | |
Western Blotting |
- 1Fixation with 4% paraformaldehyde is recommended for optimal results.
- Histology Positive Control Tissue
- Kidney
Secondary Antibodies Available
Negative Isotype Controls Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Mouse IgG2a Negative Control | MCA929 | F | 100 Tests |
![]() |
Product Specific References
References for Calcitonin Receptor antibody
-
Wookey, P.J. et al. (2008) Calcitonin receptor immunoreactivity associated with specific cell types in diseased radial and internal mammary arteries.
Histopathology. 52 (5): 605-12. -
Silvestris, F. et al. (2008) Expression and function of the calcitonin receptor by myeloma cells in their osteoclast-like activity in vitro.
Leuk Res. 32 (4): 611-23. -
Wookey, P.J. et al. (2009) The elevated expression of calcitonin receptor by cells recruited into the endothelial layer and neo-intima of atherosclerotic plaque.
Histochem Cell Biol. 132: 181-9. -
Wookey, P.J. et al. (2012) The expression of calcitonin receptor detected in malignant cells of the brain tumour glioblastoma multiforme and functional properties in the cell line A172.
Histopathology. 60 (6): 895-910. -
Lesclous, P. et al. (2009) Bisphosphonate-associated osteonecrosis of the jaw: a key role of inflammation?
Bone. 45 (5): 843-52. -
Ostrovskaya, A. et al. (2019) Expression and activity of the calcitonin receptor family in a sample of primary human high-grade gliomas.
BMC Cancer. 19 (1): 157. -
Cappagli, V. et al. (2017) Calcitonin receptor expression in medullary thyroid carcinoma.
PeerJ. 5: e3778.
Fluorescent Spectraviewer
Watch the Tool Tutorial Video ▸
How to Use the Spectraviewer?
Watch the Tool Tutorial Video ▸
- Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
- Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
- Select the lasers and filters you wish to include
- Select combined or multi-laser view to visualize the spectra