c-Fos antibody | rAB01/1D11
Mouse anti Human c-Fos
- Product Type
- Monoclonal Antibody
- Clone
- rAB01/1D11
- Isotype
- IgG2a
- Specificity
- c-Fos
Antibody Quality and Performance Guarantee
MCA6440GA
| Mouse anti Human c-Fos antibody, clone rAB01/1D11 recognizes the proto-oncogene c-Fos, also known as FBJ murine osteosarcoma viral (v-fos) oncogene homolog, G0/G1 switch regulatory protein 7 activator protein 1 or cellular oncogene c-fos. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death (provided by RefSeq, Jul 2008). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified recombinant IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Source
- CHO-S
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli-derived recombinant protein, amino acids 1-380 of human c-Fos
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1,000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- UniProt
- P01100
- Entrez Gene
- FOS
- GO Terms
- GO:0002755 MyD88-dependent toll-like receptor signaling pathway
- GO:0002756 MyD88-independent toll-like receptor signaling pathway
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0003704 specific RNA polymerase II transcription factor activity
- GO:0006306 DNA methylation
- GO:0006954 inflammatory response
- GO:0007179 transforming growth factor beta receptor signaling pathway
- GO:0008063 Toll signaling pathway
- GO:0010843 promoter binding
- View More GO Terms
- GO:0034130 toll-like receptor 1 signaling pathway
- GO:0034134 toll-like receptor 2 signaling pathway
- GO:0034138 toll-like receptor 3 signaling pathway
- GO:0034142 toll-like receptor 4 signaling pathway
- GO:0034614 cellular response to reactive oxygen species
- GO:0045087 innate immune response
- GO:0051090 regulation of transcription factor activity
- GO:0051403 stress-activated MAPK cascade
- GO:0060395 SMAD protein signal transduction
- GO:0070412 R-SMAD binding
MCA6440GA
64612315
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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