CD1w2 antibody | CC13
Mouse anti Bovine CD1w2 antibody, clone CC13 recognises the bovine CD1w2 cell surface antigen, a glycoprotein heterodimer of 12 kDa and 46 kDa. CD1w2 is expressed by cortical thymocytes and a minority of medullary thymocytes, with a pattern similar to antibodies of the CD1b cluster in humans.
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Goat Sheep
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide
- Carrier Free
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- Shelf Life
- 18 months from date of despatch.
- For research purposes only
Applications of CD1w2 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells in 100ul.
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Secondary Antibodies Available
Product Specific References
References for CD1w2 antibody
Howard, C.J. et al. (1991) Summary of workshop findings for leukocyte antigens of cattle.
Vet Immunol Immunopathol. 27: 21-7.
Parsons, K.R. et al. (1991) Immunohistology of workshop monoclonal antibodies to the bovine homologue of CD1.
Vet Immunol Immunopathol. 27: 201-6.
Parsons, K.R. and MacHugh, N.D. (1991) Individual antigens of cattle. Bovine CD1 (BoCD1).
Vet Immunol Immunopathol. 27: 37-41.
Hopkins, J. and Dutia, B.M. (1991) Workshop studies on the ovine CD1 homologue.
Vet Immunol Immunopathol. 27: 97-9.
Pinchuk, L.M. et al. (2003) Bovine dendritic cells generated from monocytes and bone marrow progenitors regulate immunoglobulin production in peripheral blood B cells.
Comp Immunol Microbiol Infect Dis. 26: 233-49.
Bujdoso, R. et al. (1989) Characterization of sheep afferent lymph dendritic cells and their role in antigen carriage.
J Exp Med. 170: 1285-301.