Bovine Immune Cell Biomarker Poster Bovine Immune Cell Biomarker Poster

Biomarker expression chart listing key cell surface markers expressed on cattle leukocytes, a guide to aid defining bovine immune cell populations.

 

Overview

The Bio-Rad bovine research antibody range offers monoclonal bovine antibodies, ELISAs, and recombinant proteins to study immune responses in cattle.

A thorough understanding of the bovine immune response is critical for assessing the general health of cattle and measuring the impact of various diseases, particularly those that affect meat and milk production.

Our anti-bovine antibodies are available with a range of conjugates and tested for reactivity to bovine markers. They are suitable for a range of applications including flow cytometry, western blotting, immunohistochemistry, immunofluorescence, immunoprecipitation, and ELISA. Each is performance guaranteed for the applications listed on the product datasheet.

Animal models have been a constant feature in modern evidence based medicine. The first empirical discoveries on the biology of human health and the latest cures for complex diseases have scientific foundations in animal models, and they continue to be important in the advancement of scientific discovery and improved human healthcare.

An example is research into tuberculosis (TB), which is a leading cause of death around the world. A significant proportion of cases are classified as drug-resistant (WHO Global tuberculosis report 2018a), highlighting the urgent need to develop vaccines and diagnostic reagents to treat TB.

Bovine tuberculosis represents one of several animal models for human tuberculosis. The pathogenesis, similarity in the latent state of the infection, and resulting innate immune responses, make bovine TB a suitable model in TB vaccine development.

The reagents manufactured by Bio-Rad enable TB research by providing the tools to profile the cells of the immune system and carry out immune function analysis.



Review: The role of Cytokines in Bovine Tuberculosis

Review: The role of Cytokines in Bovine Tuberculosis

Read more about the role of cytokines in bovine tuberculosis in a review article written by Shelley Rhodes, Member of the TB Research Group and IFNy Test Consultant, Animal Health and Veterinary Laboratories Agency.

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Identifying the Immunological Correlates of Protection in Ruminants

Identifying the Immunological Correlates of Protection in Ruminants

Read how researchers at the Moredun Research Institute and The Roslin Institute are collaborating on a project to develop and characterize immunological reagents for cattle and sheep.

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Harnessing & Directing the Bovine Innate Immune System: Importance of TLRs

Harnessing & Directing the Bovine Innate Immune System: Importance of TLRs

Find out more about the bovine toll-like receptor family and our current knowledge about signaling mechanisms in this article written by Professor Dirk Werling, Royal Veterinary College, UK.

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Bovine Adaptive and Innate Immunity

Bovine Adaptive and Innate Immunity​

Here is an introduction to the bovine immune system in two brief articles that introduce both the bovine adaptive and innate systems. They give an overview of the key cell types, the cytokine responses, and also draw comparisons to murine and human immunology.

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