Calcitonin Receptor Antibody | 31/01-1H10-4-1-14

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  • Mouse anti Human Calcitonin Receptor
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Monoclonal Antibody
  • Clone
    31/01-1H10-4-1-14
  • Isotype
    IgG2a
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA2191C, E, F, IF, P *, WBdatasheet pdfdatasheet pdf0.1 mg
    MCA2191
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
    -
    • Mouse anti Human calcitonin recptor antibody, clone 31/01-1H10-4-1-14 recognizes the human calcitonin receptor, a membrane protein with seven transmembrane domains that is coupled to G protein messenger systems. Mouse anti Human calcitonin recptor antibody, clone 31/01-1H10-4-1-14 recognizes an epitope within the cytoplasmic domain that is common to both C1a and C1b human isoforms.

      Calcitonin receptor is expressed in kidney, central and peripheral nervous systems and on osteoclasts. It is also expressed in a number of tissues during the development of the embryo and may be important in foetal morphogenesis.
    • Intended Use
    • Target Species
      Human
    • Species Cross-Reactivity
      Target SpeciesCross Reactivity
      Rabbityes
      N.B. Antibody reactivity and working conditions may vary between species.
    • Product Form
      Purified IgG - liquid
    • Reconstitution
    • Preparation
      Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
    • Preservative Stabilisers
      0.09%Sodium Azide
    • Immunogen
      Synthetic peptide, DIPIYICHQELRNEPANN, derived from the cytoplasmic domain of human calcitonin receptor.
    • Purity
    • Approx. Protein Concentrations
      IgG concentration 1.0 mg/ml
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
      Phosphate buffered saline
    • Fusion Partners
      Spleen cells from immunised mice were fused with cells of the mouse SP2/0 myeloma cell line.
    • Storage
      Store at +4oC or at -20oC if preferred.

      This product should be stored undiluted.

      Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      18 months from date of despatch.
    • GO Terms
      elevation of cytosolic calcium ion concentration
      response to glucocorticoid stimulus
      integral to plasma membrane
      activation of adenylate cyclase activity by G-protein signaling pathway
      calcitonin binding
      positive regulation of adenylate cyclase activity
      protein binding
      calcitonin receptor activity
    • UniProt
    • Entrez Gene
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      ELISA1/10001/5000
      Flow Cytometry
      Immunofluorescence
      Immunohistology - Frozen
      Western Blotting
      Immunohistology - Paraffin(1)1/501/500
      (1)
      Fixation with 4% paraformaldehyde is recommended for optimal results.

    • Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
      Kidney
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional Calcitonin Receptor Antibody Formats

    Formats Clone Applications Sizes available
    Calcitonin Receptor Antibody : Purified 31/01-1H10-4-1-14 C, E, F, IF, P *, WB 0.1 mg
    • Copyright © 2016 Bio-Rad

    Recommended Secondary Antibody

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      Recommended Negative Isotype Control

        DescriptionProduct CodePack SizeApplicationsList PriceQuantity
        Mouse IgG2a Negative ControlMCA929100 TestsF
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        Useful Reagents

          Recommended Positive Controls

            Histology Controls

              Kidney

              References

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