CD309 antibody | CH-11
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Mouse anti CD309
- Product Type
- Monoclonal Antibody
- Clone
- CH-11
- Isotype
- IgG1
- Specificity
- CD309
Antibody Quality and Performance Guarantee
| Mouse anti CD309, Clone CH-11, recognizes both mouse and human vascular endothelial growth factor receptor 2 (VEGF R2), also known as FLK-1 or Kinase insert domain receptor. CD309 is one of three VEGF receptor kinases which play an important role in angiogenesis. VEGF receptors are characterised by a cytoplasmic split-kinase domain and seven extracellular immunoglobulin domains. |
- Target Species
- Mouse
- Species Cross-Reactivity
-
Target Species Cross Reactivity Human - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium azide
- Immunogen
- Recombinant fragment corresponding to amino acids 1158 to 1345 within the intracellular region of mouse CD309.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
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| Immunohistology - Paraffin 1 | |
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| Western Blotting | |
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.EDTA pH8.0 is recommended for this purpose.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Histology Positive Control Tissue
- Placenta
- Western Blotting
- Clone CH-11 detects bands of approximately 200kDa and 230kDa in HUVEC cell lysates.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Antigen Retrieval Buffer, pH8.0 | BUF025A | P | 500 ml | Log in | |||
| List Price | Your Price | ||||||
| Log in | |||||||
| Description | Antigen Retrieval Buffer, pH8.0 | ||||||
References for CD309 antibody
-
Qiang, L. et al. (2013) Expression of miR-126 and miR-508-5p in endothelial progenitor cells is associated with the prognosis of chronic heart failure patients.
Int J Cardiol. 168 (3): 2082-8. -
Malini, E. et al. (2015) Role of LIMP-2 in the intracellular trafficking of β-glucosidase in different human cellular models.
FASEB J. 29 (9): 3839-52. -
Dardis, A. et al. (2016) Altered localization and functionality of TAR DNA Binding Protein 43 (TDP-43) in niemann- pick disease type C.
Acta Neuropathol Commun. 4 (1): 52.
- Synonyms
- VEGFR 2
- RRID
- AB_2132486
- UniProt
- P35918
- P35968
- Entrez Gene
- Kdr
- KDR
- GO Terms
- GO:0001525 angiogenesis
- GO:0001541 ovarian follicle development
- GO:0001570 vasculogenesis
- GO:0001945 lymph vessel development
- GO:0002053 positive regulation of mesenchymal cell proliferation
- GO:0019838 growth factor binding
- GO:0005021 vascular endothelial growth factor receptor activity
- GO:0005887 integral to plasma membrane
- GO:0005524 ATP binding
- View More GO Terms
- GO:0006468 protein phosphorylation
- GO:0016477 cell migration
- GO:0030097 hemopoiesis
- GO:0043129 surfactant homeostasis
- GO:0045165 cell fate commitment
- GO:0045446 endothelial cell differentiation
- GO:0048286 lung alveolus development
- GO:0048469 cell maturation
- GO:0048754 branching morphogenesis of a tube
- GO:0055074 calcium ion homeostasis
- GO:0001938 positive regulation of endothelial cell proliferation
- GO:0004716 receptor signaling protein tyrosine kinase activity
- GO:0005178 integrin binding
- GO:0008360 regulation of cell shape
- GO:0051879 Hsp90 protein binding
- GO:0010595 positive regulation of endothelial cell migration
- GO:0044419 interspecies interaction between organisms
- GO:0050927 positive regulation of positive chemotaxis
- GO:0051894 positive regulation of focal adhesion assembly
OBT1170
150353
158042
161025
161461
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