CD38 Antibodies

CD38 : Marker Details

Synonyms

T10, ADP-ribosyl cyclase

Functions and Associated Signalling Pathways

Synthesis of cyclic ADP ribose. Calcium signaling and cell activation

Cellular Localization

Cell membrane

Cellular Expression

Common Myeloid Precursor, Granulocyte Monocyte Precursor, Megakaryocyte Erythroid Precursor, T Cell, Plasmablast, Plasma Cell, B2 Cell, Natural Killer Cell, Dendritic Cell

Receptor Type

Glycoprotein

Ligand

CD31, ATP

What is CD38?

CD38 is a multifunctional glycoprotein found on the surface of many immune cells, including B cells, T cells, and natural killer (NK) cells. It plays several roles in the body:

Functions

  • Enzymatic activity: CD38 catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+, which is crucial for calcium signaling within cells
  • Receptor function: it can act as a receptor, binding to CD31 on T cells and triggering the production of cytokines
  • Cell adhesion: CD38 is involved in cell adhesion processes, helping cells to interact and communicate

Applications in Research

  • Immunology: studying immune responses and mechanisms
  • Cancer research: CD38 is used as a prognostic marker for chronic lymphocytic leukemia

Clinical Significance

  • Disease marker: CD38 is a marker for various diseases, including leukemia and autoimmune conditions

Anti CD38 Antibodies

Our range of CD38 antibodies come in a large variety of different formats (including StarBright Dyes) and to a number of target species. These antibodies can be used for applications including flow cytometry, immunohistochemistry, and immunoprecipitation.

Please use the filters to sort the attributes in the table below in order to find the antibody that fits your exact requirements. If you need any further assistance please do not hesitate to contact us.

Our CD38 Antibody Range

    DescriptionSpecificityTargetFormatHostIsotypeClone Applications Citations Product Type Code Validation Types