CD68 is a pan-macrophage marker making CD68 antibodies an essential tool in macrophage research.
CD68 is a 110-kDa glycoprotein highly expressed by monocytes and tissue macrophages, including Kupffer cells, microglia, histiocytes and osteoclasts. CD68 is also present to a lesser extent on dendritic cells and peripheral blood granulocytes. Being classified as a member of the scavenger receptor family, typical functions of CD68 include clearance of cellular debris, promotion of phagocytosis, and the mediation, recruitment and activation of macrophages. CD68 is also a member of the lysosome associated membrane protein (LAMP) family, where CD68 predominantly localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface.
Most popular CD68 antibody options at a glance, click here to view all CD68 antibodies.
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In addition to CD68, Bio-Rad also offers a wide range of other macrophage markers such as:
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