Compiling key proteins involved in key signaling pathways: cGAS-STING, EGF R, mTOR, NF-kB, and PI3/AKT pathways.
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14-3-3 proteins are of key research interest as they regulate many cellular processes and are highly conserved. There are seven mammalian isoforms of 14-3-3; beta, gamma, zeta, epsilon, tau, eta, and sigma, while the alpha and delta isoforms are phosphorylated.
Bio-Rad’s anti-14-3-3 antibodies are part of our wide Cell Signaling antibody range.
14-3-3 proteins form dimers that regulate many cellular processes through their interaction with a wide variety of ligands such as
Research studies suggest that 14-3-3 isoforms are differentially regulated in various diseases, particularly in: