Bio-Rad has an extended 14-3-3 antibody range with specificities to all major mammalian isoforms. The comprehensive range of quality 14-3-3 antibodies includes pan-specific and phospho-specific antibodies (pSer185 & pSer58). We also offer a 14-3-3 isoform panel, ideal for determining which isoform is present in your sample. Manufactured to ISO 9001 standards, our antibodies are guaranteed to perform to specification in a wide range of applications.
|Specificity||Host Species||Clone||Format||Pack Size||Application||Product Code|
|14-3-3 (pSER185)||Sheep||pAb||Purified||0.1 mg||WB||AHP1049|
|14-3-3 BETA||Rabbit||pAb||Serum||0.1 ml||E,P,WB||AHP1044|
|14-3-3 EPSILON (C-TERMINAL)||Rabbit||pAb||Serum||0.1 ml||E,P,WB||AHP1045|
|14-3-3 EPSILON (N-TERMINAL)||Rabbit||pAb||Serum||0.1 ml||E,P,WB||AHP1048|
|14-3-3 ETA||Rabbit||pAb||Serum||0.1 ml||P ,WB||AHP1046|
|14-3-3 SIGMA||Rabbit||pAb||Serum||0.1 ml||WB||AHP1050|
|14-3-3 TAU/THETA||Rabbit||pAb||Serum||0.1 ml||E, P,WB||AHP1051|
|14-3-3 ZETA||Rabbit||pAb||Serum||0.1 ml||E,P,WB||AHP1052|
|14-3-3 Isoform Panel||Rabbit||pAb||Serum||0.025mlx7||E,P,WB||PAN017|
14-3-3 proteins are of key research interest as they regulate many cellular processes and are highly conserved. There are seven mammalian isoforms of 14-3-3; beta, gamma, zeta, epsilon, tau, eta, and sigma, while the alpha and delta isoforms are phosphorylated.
14-3-3 proteins form dimers that regulate many cellular processes through their interaction with a wide variety of ligands such as
Research studies suggest that 14-3-3 isoforms are differentially regulated in various diseases, particularly in: