Respiratory Syncytial Virus Fusion Protein antibody | 0651

Mouse anti Respiratory Syncytial Virus Fusion Protein

Product Type
Monoclonal Antibody
Clone
0651
Isotype
IgG2a
Specificity
Respiratory Syncytial Virus Fusion Protein

Product Code Applications Pack Size List Price Your Price Qty
MCA2652
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E IF 0.1 mg loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Mouse anti Respiratory syncitial virus antibody, clone 0651 detects the fusion protein of human respiratory syncytial virus (RSV), groups A and B. RSV is a negative-sense, single-stranded RNA virus and is a member of the Paramyxoviridae family. RSV causes respiratory tract infections in patients of all ages, but particularly affects infants and the immunosuppressed.

RSV encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a glycoprotein (G) known as the attachment protein, and a fusion (F) protein. The F protein directs fusion of viral and cellular membranes, resulting in viral penetration, and can lead to the formation of syncytia.

The F protein is thought to be the principal antigen responsible for inducing an immune response.

Target Species
Viral
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1%Sodium Azide (NaN3)
Immunogen
Fusion protein of the human Respiratory Synctial Virus.
Approx. Protein Concentrations
IgG concentration 0.1mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/20 1/200
Immunofluorescence 1/10 1/50
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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References for Respiratory Syncytial Virus Fusion Protein antibody

  1. Schlender, J. et al. (2003) Respiratory syncytial virus (RSV) fusion protein subunit F2, not attachment protein G, determines the specificity of RSV infection.
    J Virol. 77 (8): 4609-16.
  2. Kim, Y.K. et al. (2007) Genetic variability of the fusion protein and circulation patterns of genotypes of the respiratory syncytial virus.
    J Med Virol. 79 (6): 820-8.

Further Reading

  1. Cianci, C. et al. (2005) Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor.
    J Antimicrob Chemother. 55 (3): 289-92.

Synonyms
RSV
RRID
AB_844557