Respiratory Syncytial Virus Fusion Protein antibody | 0651
No associated image currently available
Mouse anti Respiratory Syncytial Virus Fusion Protein
- Product Type
- Monoclonal Antibody
- Clone
- 0651
- Isotype
- IgG2a
- Specificity
- Respiratory Syncytial Virus Fusion Protein
Antibody Quality and Performance Guarantee
| Mouse anti Respiratory syncitial virus antibody, clone 0651 detects the fusion protein of human respiratory syncytial virus (RSV), groups A and B. RSV is a negative-sense, single-stranded RNA virus and is a member of the Paramyxoviridae family. RSV causes respiratory tract infections in patients of all ages, but particularly affects infants and the immunosuppressed. RSV encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a glycoprotein (G) known as the attachment protein, and a fusion (F) protein. The F protein directs fusion of viral and cellular membranes, resulting in viral penetration, and can lead to the formation of syncytia. The F protein is thought to be the principal antigen responsible for inducing an immune response. |
- Target Species
- Viral
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.1% Sodium Azide (NaN3) - Immunogen
- Fusion protein of the human Respiratory Synctial Virus.
- Approx. Protein Concentrations
- IgG concentration 0.1mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1/20 | 1/200 |
| Immunofluorescence | |
1/10 | 1/50 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
References for Respiratory Syncytial Virus Fusion Protein antibody
-
Schlender, J. et al. (2003) Respiratory syncytial virus (RSV) fusion protein subunit F2, not attachment protein G, determines the specificity of RSV infection.
J Virol. 77 (8): 4609-16. -
Kim, Y.K. et al. (2007) Genetic variability of the fusion protein and circulation patterns of genotypes of the respiratory syncytial virus.
J Med Virol. 79 (6): 820-8.
Further Reading
-
Cianci, C. et al. (2005) Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor.
J Antimicrob Chemother. 55 (3): 289-92.
- Synonyms
- RSV
- RRID
- AB_844557
MCA2652
150531
162899
164778
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
View more products with RESPIRATORY SYNCYTIAL VIRUS specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Viral ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up