Feline Immunodeficiency Virus p24 antibody | NM3-6A9
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Mouse anti Feline immunodeficiency virus p24 antibody, clone NM3-6A9 recognizes feline immunodeficiency virus (FIV) p24 gag capsid protein, derived from the p50 GAG polyprotein. The p24 capsid protein forms the conical viral core encapsulating the genomic RNA-nucleocapsid complex and is involved in viral packaging and subsequent release from infected cells. FIV is a lentivirus infecting many domestic and wild cat species, resulting in a progressive immunodeficiency disease bearing a number of parallels with HIV-1 infection in man (Sparger et al. 1989).
Mouse anti Feline immunodeficiency virus p24 antibody, clone NM3-6A9 does not recognise Feline Leukemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus.
Mouse anti feline immunodeficiency virus p24, clone NM3-6A9 recognizes a different epitope to clone PAK3-2C1.
Mouse anti Feline immunodeficiency virus p24 antibody, clone NM3-6A9 does not recognise Feline Leukemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus.
Mouse anti feline immunodeficiency virus p24, clone NM3-6A9 recognizes a different epitope to clone PAK3-2C1.
Product Details
- Target Species
- Viral
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.05% Sodium Azide (NaN3) - Immunogen
- Native, extracts
- Approx. Protein Concentrations
- 1.0mg/ml
Storage Information
- Storage
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. - Guarantee
- 12 months from date of despatch
More Information
- Regulatory
- For research purposes only
Applications of Feline Immunodeficiency Virus p24 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | 0.5 µg/well | ||
| Flow Cytometry | 1/50 | 1/100 | |
| Western Blotting | 1/25 | 1/200 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
- Western Blotting
- 4413-5107 detects a major band of approximately 24kDa
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Secondary Antibodies Available
Useful Reagents Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Mouse anti Feline Immunodeficiency Virus p24 gag | MCA2278 | C* E F* IF WB | 0.25 mg |
|
Product Specific References
Further Reading
-
Kenyon, J.C. and Lever, A.M. (2011) The molecular biology of feline immunodeficiency virus (FIV).
Viruses. 3: 2192-213. -
Luttge, B.G. and Freed, E.O. (2010) FIV Gag: virus assembly and host-cell interactions.
Vet Immunol Immunopathol. 134: 3-13. -
Willett, B.J. et al. (1997) FIV infection of the domestic cat: an animal model for AIDS.
Immunol Today. 18: 182-9.
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