Canine Distemper Virus antibody | DV2-12
Mouse anti canine distemper virus antibody, clone DV2-12 is useful for the detection of CDV in immunofluorescence procedures, in which the staining seen has a cytoplasmic pattern in infected cells. It is also effective in paraffin embedded material.
Mouse anti canine distemper virus antibody, clone DV2-12 is anti morbillivirus specific and reacts with phocine distemper virus, racoon distemper virus and human measles virus. It does not cross react with CAV2, CCV, CPI or CPV.
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Raccoon dog
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.05% Sodium Azide
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- For research purposes only
Applications of Canine Distemper Virus antibody
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
|Immunohistology - Paraffin 1|
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Serotec target unmasking fluid (STUF) product code BUF025A/B/C is recommended for this purpose.
Secondary Antibodies Available
Product Specific References
References for Canine Distemper Virus antibody
Guvenc, T. et al. (2008) Immunohistochemical distribution of alpha B-crystallin in the cerebellum of dogs infected with canine distemper virus.
Acta Vet Hung. 56: 117-23.
Headley, S.A. et al. (2009) Diagnostic exercise: Tyzzer's disease, distemper, and coccidiosis in a pup. .
Vet Pathol. 46: 151-4.
Headley, S.A. et al. (2009) Molecular detection of Canine distemper virus and the immunohistochemical
characterization of the neurologic lesions in naturally occurring old dog
J Vet Diagn Invest. 21: 588-97.
Bathen-Noethen, A. et al. (2008) Magnetic resonance imaging findings in acute canine distemper virus infection.
J Small Anim Pract. 49: 460-7.
Kyöstilä, K. et al. (2012) A SEL1L mutation links a canine progressive early-onset cerebellar ataxia to the endoplasmic reticulum-associated protein degradation (ERAD) machinery.
PLoS Genet. 8 (6): e1002759.
Headley, S.A. and Sukura, A. (2009) Naturally occurring systemic canine distemper virus infection in a pup
Braz J Vet Pathol 2: 95-101.
Kubo, M. et al. (2010) Meningoencephalitis associated with Sarcocystis spp. in a free-living Japanese raccoon dog (Nyctereutes procyonoides viverrinus).
J Comp Pathol. 143: 185-9.
Sánchez-Migallón Guzmán, D. et al. (2008) Aleutian disease serology, protein electrophoresis, and pathology of the European mink (Mustela lutreola) from Navarra, Spain.
J Zoo Wildl Med. 39: 305-13.
Szentiks, C.A. et al. (2013) Polar bear encephalitis: establishment of a comprehensive next-generation pathogen analysis pipeline for captive and free-living wildlife.
J Comp Pathol. 2014 May;150(4):474-88.
Rentería-Solís, Z. et al. (2014) Canine distemper outbreak in raccoons suggests pathogen interspecies transmission amongst alien and native carnivores in urban areas from Germany.
Vet Microbiol. 174 (1-2): 50-9.
Woo, G.H. et al. (2010) Canine distemper virus infection in fennec fox (Vulpes zerda).
J Vet Med Sci. 72 (8): 1075-9.
Spitzbarth, I. et al. (2010) Immunohistochemical characterization of inflammatory and glial responses in a case of necrotizing leucoencephalitis in a French bulldog.
J Comp Pathol. 142 (2-3): 235-41.
Liang, C.T. et al. (2007) A non-biotin polymerized horseradish-peroxidase method for the immunohistochemical diagnosis of canine distemper.
J Comp Pathol. 136 (1): 57-64.
Bak, W.E. and Woo, G.H. (2016) Canine Distemper in Albino Ferrets (Mustela putorius furo)
J comp Pathol. 154: 121