Canine Distemper Virus antibody | DV2-12
Mouse anti canine distemper virus antibody, clone DV2-12 is useful for the detection of CDV in immunofluorescence procedures, in which the staining seen has a cytoplasmic pattern in infected cells. It is also effective in paraffin embedded material.
Mouse anti canine distemper virus antibody, clone DV2-12 is anti morbillivirus specific and reacts with phocine distemper virus, racoon distemper virus and human measles virus. It does not cross react with CAV2, CCV, CPI or CPV.
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Raccoon dog
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
- 12 months from date of despatch
- For research purposes only
Applications of Canine Distemper Virus antibody
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
|Immunohistology - Paraffin 1|
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Serotec target unmasking fluid (STUF) product code BUF025A/B/C is recommended for this purpose.
Secondary Antibodies Available
Product Specific References
References for Canine Distemper Virus antibody
Guvenc, T. et al. (2008) Immunohistochemical distribution of alpha B-crystallin in the cerebellum of dogs infected with canine distemper virus.
Acta Vet Hung. 56: 117-23.
Headley, S.A. et al. (2009) Diagnostic exercise: Tyzzer's disease, distemper, and coccidiosis in a pup. .
Vet Pathol. 46: 151-4.
Headley, S.A. et al. (2009) Molecular detection of Canine distemper virus and the immunohistochemical
characterization of the neurologic lesions in naturally occurring old dog
J Vet Diagn Invest. 21: 588-97.
Bathen-Noethen, A. et al. (2008) Magnetic resonance imaging findings in acute canine distemper virus infection.
J Small Anim Pract. 49: 460-7.
Kyöstilä, K. et al. (2012) A SEL1L mutation links a canine progressive early-onset cerebellar ataxia to the endoplasmic reticulum-associated protein degradation (ERAD) machinery.
PLoS Genet. 8 (6): e1002759.
Headley, S.A. and Sukura, A. (2009) Naturally occurring systemic canine distemper virus infection in a pup
Braz J Vet Pathol 2: 95-101.
Kubo, M. et al. (2010) Meningoencephalitis associated with Sarcocystis spp. in a free-living Japanese raccoon dog (Nyctereutes procyonoides viverrinus).
J Comp Pathol. 143: 185-9.
Sánchez-Migallón Guzmán, D. et al. (2008) Aleutian disease serology, protein electrophoresis, and pathology of the European mink (Mustela lutreola) from Navarra, Spain.
J Zoo Wildl Med. 39: 305-13.
Szentiks, C.A. et al. (2013) Polar bear encephalitis: establishment of a comprehensive next-generation pathogen analysis pipeline for captive and free-living wildlife.
J Comp Pathol. 2014 May;150(4):474-88.
Rentería-Solís, Z. et al. (2014) Canine distemper outbreak in raccoons suggests pathogen interspecies transmission amongst alien and native carnivores in urban areas from Germany.
Vet Microbiol. 174 (1-2): 50-9.
Woo, G.H. et al. (2010) Canine distemper virus infection in fennec fox (Vulpes zerda).
J Vet Med Sci. 72 (8): 1075-9.
Spitzbarth, I. et al. (2010) Immunohistochemical characterization of inflammatory and glial responses in a case of necrotizing leucoencephalitis in a French bulldog.
J Comp Pathol. 142 (2-3): 235-41.
Liang, C.T. et al. (2007) A non-biotin polymerized horseradish-peroxidase method for the immunohistochemical diagnosis of canine distemper.
J Comp Pathol. 136 (1): 57-64.
Bak, W.E. and Woo, G.H. (2016) Canine Distemper in Albino Ferrets (Mustela putorius furo)
J comp Pathol. 154: 121
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