Insulin antibody | 2D11
Mouse anti Pig Insulin
- Product Type
- Monoclonal Antibody
- Clone
- 2D11
- Isotype
- IgG1
- Specificity
- Insulin
Antibody Quality and Performance Guarantee
| Mouse anti Porcine insulin antibody, clone 2D11 recognizes porcine insulin, a hormone involved in glucose homeostasis. |
- Target Species
- Pig
- Species Cross-Reactivity
-
Target Species Cross Reactivity Human Bovine - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Native porcine insulin.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
||
| Immunohistology - Paraffin | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
References for Insulin antibody
-
Cho, B. et al. (2018) Generation of insulin-deficient piglets by disrupting INS gene using CRISPR/Cas9 system.
Transgenic Res. 27 (3): 289-300. -
Cho, B. et al. (2019) Production of genetically modified pigs expressing human insulin and C-peptide as a source of islets for xenotransplantation.
Transgenic Res. 28 (5-6): 549-59.
- RRID
- AB_2126654
- UniProt
- P01315
- Entrez Gene
- INS
- GO Terms
- GO:0005576 extracellular region
- GO:0005179 hormone activity
- GO:0006006 glucose metabolic process
- GO:0030335 positive regulation of cell migration
- GO:0031954 positive regulation of protein autophosphorylation
- GO:0045740 positive regulation of DNA replication
- GO:0046628 positive regulation of insulin receptor signaling pathway
- GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
5330-1330
162868
167016
1805
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
View more products with INSULIN specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Pig ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up