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CD200R1/CD200R1L antibody | PCT1

Mouse anti Pig CD200R1/CD200R1L

Product Type
Monoclonal Antibody
Clone
PCT1
Isotype
IgG1
Specificity
CD200R1/CD200R1L

Product Code Applications Pack Size List Price Your Price Qty
MCA6444GA
Datasheet Datasheet
SDS Safety Datasheet SDS
F 0.1 mg loader
List Price Your Price
loader

Mouse anti-Pig CD200R1/CD200R1L antibody, clone PCT1, recognizes both pig CD200R1 and CD200R1L.

CD200R1 and CD200R1L are paired receptors involved in the regulation of immune cell activation. In pigs, these receptors are expressed on various myeloid cells, including monocytes and also a subset of lymphocytes, and play a crucial role in modulating immune responses. CD200R1 acts as an inhibitory receptor, while CD200R1L functions as an activating receptor, together maintaining a balance in immune cell signaling.

Mouse anti-Pig CD200R1/CD200R1L antibody, clone PCT1, has been pivotal in characterizing the expression of these receptors on porcine immune cells. This antibody has enabled detailed analysis of CD200R1 and CD200R1L expression, revealing their distinct roles in immune regulation. Mouse anti-Pig CD200R1/CD200R1L antibody is a valuable tool for studying immune modulation and developing therapeutic strategies in porcine models ( Poderoso et al. 2019).

Target Species
Pig
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
This product is sold under a license from Spanish National Research Council (CSIC).

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry 1/25 1/200
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul

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References for CD200R1/CD200R1L antibody

  1. Poderoso, T. et al. (2019) Analysis of the expression of porcine CD200R1 and CD200R1L by using newly developed monoclonal antibodies
    Dev Comp Immunol. 100
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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