Troponin I antibody | C5
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Mouse anti Troponin I (Cardiac/Skeletal)
- Product Type
- Monoclonal Antibody
- Clone
- C5
- Isotype
- IgG2b
- Specificity
- Troponin I
- Region
- (CARDIAC/SKELETAL)
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| Mouse anti Troponin I (Cardiac/Skeletal) antibody, clone C5 reacts with cardiac and skeletal troponin I. Mouse anti Troponin I (Cardiac/Skeletal) antibody, clone C5 recognizes an epitope between amino acids 186-192 of cardiac troponin I.Troponin I is 1 of 3 subunits that constitute the troponin complex which plays an important role in the regulation of skeletal and cardiac muscle contraction. It is presented in cardiac tissue by a single isoform with a molecular weight of 29 kDa and is known as a specific marker for cardiac tissue damage. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Cat Rabbit Dog Pig Rat Goat Bovine Fish - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified Ig - liquid
- Preparation
- Purified Ig prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Free human cardiac troponin I.
- Approx. Protein Concentrations
- 1 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
||
| Western Blotting | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
- RRID
- AB_616916
- UniProt
- P19429
- P19237
- P48788
- Entrez Gene
- TNNI1
- TNNI3
- TNNI2
- GO Terms
- GO:0001570 vasculogenesis
- GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions
- GO:0003779 actin binding
- GO:0005829 cytosol
- GO:0005861 troponin complex
- GO:0006874 cellular calcium ion homeostasis
- GO:0019855 calcium channel inhibitor activity
- GO:0019901 protein kinase binding
- GO:0019904 protein domain specific binding
- View More GO Terms
- GO:0030049 muscle filament sliding
- GO:0030172 troponin C binding
- GO:0031014 troponin T binding
- GO:0032780 negative regulation of ATPase activity
- GO:0048306 calcium-dependent protein binding
- GO:0055010 ventricular cardiac muscle tissue morphogenesis
- GO:0060048 cardiac muscle contraction
- GO:0003009 skeletal muscle contraction
- GO:0005634 nucleus
- GO:0045941 positive regulation of transcription
View more products with TROPONIN specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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