Mouse anti Human Tg, Clone 56.7D7 recognizes human thyroglobulin, a ~660 kDa homodimer produced by the thyroid gland, specifically in the thyrocytes, and stored within the follicular lumen. Thyroglobulin is the precursor of the iodated thyroid hormones thyroxine (T4) and triiodothyronine (T3). These hormones affect protein, fat and carbohydrate metabolism. Defects in thyroglobulin production can lead to goiter, and increased susceptibility to autoimmune thyroid type 3 diseases, such as Graves disease and Hashimoto thyroiditis.
Mouse anti Human Tg, Clone 56.7D7 shows negligible cross reactivity (<0.01%) with human serum albumin, human immunoglobulin, T3 and T4.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- 1 x 1011 L/mole
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Thyroglobulin antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available