Tenascin antibody | T2H5
Tenascin has been implicated in the guidance of migrating neurons and axons during development and neuronal regeneration. It promotes cortical neuron outgrowths and is an important component of the wound matrix and scar formation.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Purified protein from human mammary tumour.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunized Balb/c mice were fused with cells of the Sp2/0-Ag14 mouse myeloma cell line.
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- P24821 Related reagents
- Entrez Gene
- TNC Related reagents
- GO Terms
- GO:0005102 receptor binding
- GO:0007155 cell adhesion
- GO:0007165 signal transduction
- GO:0005615 extracellular space
- GO:0009611 response to wounding
- GO:0045545 syndecan binding
- For research purposes only
Applications of Tenascin antibody
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
|Immunohistology - Paraffin 1|
- 1 Staining may be enhanced using trypsin digestion or heat mediated antigen retrieval using sodium citrate buffer pH 6.0.
- This product is suitable for use in direct ELISA applications, 8640-0502 may be used as a standard.
- Histology Positive Control Tissue
- Human tonsil.
Secondary Antibodies Available
Product Specific References
Schalkwijk, J. et al. (1991) Tenascin expression in human dermis is related to epidermal proliferation.
Am J Pathol. 139 (5): 1143-50.
References for Tenascin antibody
Verstraeten, A.A. et al. (1992) Tenascin expression in basal cell carcinoma.
Br J Dermatol. 127 (6): 571-4.
Le Poole, I.C. et al. (1997) Tenascin is overexpressed in vitiligo lesional skin and inhibits melanocyte adhesion.
Br J Dermatol. 137 (2): 171-8.
Milz, S. et al. (2007) An immunohistochemical study of the triangular fibrocartilage complex of the wrist: regional variations in cartilage phenotype.
J Anat. 211: 1-7.
Päiväniemi, O, et al. (2006) Tenascin is expressed in post-transplant obliterative bronchiolitis.
Transplant Proc. 38: 2694-6.
Nakamura, Y. et al. (2004) Ets-1 regulates TNF-alpha-induced matrix metalloproteinase-9 and tenascin expression in primary bronchial fibroblasts.
J Immunol. 172: 1945-52.
Milz, S. et al. (2002) Expression of a wide range of extracellular matrix molecules in the tendon and trochlea of the human superior oblique muscle.
Invest Ophthalmol Vis Sci. 43: 1330-4.