TCR Alpha antibody | 3A8
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Mouse anti Human TCR Alpha Chain
- Product Type
- Monoclonal Antibody
- Clone
- 3A8
- Isotype
- IgG2a
- Specificity
- TCR Alpha
Antibody Quality and Performance Guarantee
| Mouse anti Human TCR alpha chain antibody, clone 3A8 reacts with the alpha chain constant region found on all alpha/beta TCR bearing T-lymphocytes. It reacts with 92-98% of all CD3 + peripheral blood lymphocytes. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared from ascites by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin - Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Pack Size: 50 µg
Store at +4°C. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Pack Size: 0.1 mg
Store at +4oC.
DO NOT FREEZE
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
DO NOT FREEZE
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | |||
| Immunohistology - Frozen |  |
||
| Immunoprecipitation | |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Further Reading
-
Minami, Y. et al. (1987) Building a multichain receptor: synthesis, degradation, and assembly of the T-cell antigen receptor.
Proc Natl Acad Sci U S A. 84 (9): 2688-92. -
Koning, F. et al. (1988) The biosynthesis and assembly of T cell receptor alpha- and beta-chains with the CD3 complex.
J Immunol. 140 (9): 3126-34. -
van Dongen, J.J. et al. (1987) T cell receptor-CD3 complex during early T cell differentiation. Analysis of immature T cell acute lymphoblastic leukemias (T-ALL) at DNA, RNA, and cell membrane level.
J Immunol. 138 (4): 1260-9.
- RRID
- AB_322432
- UniProt
- P01848
- Entrez Gene
- TRAC
- GO Terms
- GO:0004872 receptor activity
- GO:0042605 peptide antigen binding
- GO:0005887 integral to plasma membrane
- GO:0006968 cellular defense response
- GO:0031295 T cell costimulation
- GO:0042287 MHC protein binding
- GO:0050852 T cell receptor signaling pathway
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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