STAM2 antibody | CD01-1D7
Mouse anti Human STAM2
- Product Type
- Monoclonal Antibody
- Clone
- CD01-1D7
- Isotype
- IgG1
- Specificity
- STAM2
Antibody Quality and Performance Guarantee
| Mouse anti human STAM2 antibody, clone CD01-1D7
recognizes signal transducing adaptor molecule 2, also known as Hrs-binding protein. STAM2 is a subunit of the ESCRT-0 complex and functions as a regulator of receptor signaling and trafficking. Studies have revealed that STAM2 is highly expressed in the brain and specifically localizes to the nucleus in neurons, suggesting that STAM2 might have a specific function in the nervous system (Kapuralin et al. 2015). In gastric cancer, knockdown of STAM2 inhibits cell proliferation and cell migration through affecting the JAK2/STAT3 signaling pathway (Yang et al. 2021). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli-derived recombinant protein, aa 165-525 of human STAM2
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1,000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Mouse anti Human STAM2 antibody detects a band of 66 kDa in MCF-7 cell lysates
- UniProt
- O75886
- Entrez Gene
- STAM2
- GO Terms
- GO:0005515 protein binding
- GO:0005829 cytosol
- GO:0006886 intracellular protein transport
- GO:0007173 epidermal growth factor receptor signaling pathway
- GO:0031901 early endosome membrane
- GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
MCA6419GA
100007684
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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