ROR1 antibody | 2F8

Mouse anti Human ROR1:Preservative Free

Product Type
Monoclonal Antibody
Clone
2F8
Isotype
IgG1
Specificity
ROR1

Product Code Applications Pack Size List Price Your Price Qty
MCA3305Z
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 0.1 mg loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Mouse anti Human ROR1 antibody, clone 2F8 recognizes human Inactive tyrosine-protein kinase transmembrane receptor ROR1, also known as ROR1 or Neurotrophic tyrosine kinase, receptor-related 1. ROR1 is a 908 amino acid ~120 kDa single pass type I transmembrane glycoprotein which may act as a receptor for the wnt ligand WNT5A.

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from ascites
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
None present
Immunogen
Recombinant protein corresponding to aa 294-393 of human ROR1
Approx. Protein Concentrations
Ig concentration 0.5 mg/ml
Fusion Partners
Spleen cells from Balb/c mice were fused with cells from the Sp2/0 myeloma cell line.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 0.1 10 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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Description Goat anti Mouse IgG (H/L):DyLight®680 (Multi Species Adsorbed)
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Description Goat anti Mouse IgG (H/L):DyLight®800 (Multi Species Adsorbed)
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Description Goat anti Mouse IgG (H/L):DyLight®650 (Multi Species Adsorbed)
Goat anti Mouse IgG (H/L):DyLight®550 (Multi Species Adsorbed) STAR117D550 F IF WB 0.1 mg loader
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Description Goat anti Mouse IgG (H/L):DyLight®550 (Multi Species Adsorbed)

Further Reading

  1. Zhang, S. et al. (2012) ROR1 Is Expressed in Human Breast Cancer and Associated with Enhanced Tumor-Cell Growth.
    PLoS One. 7: e31127.

RRID
AB_2238724
UniProt
Q01973
Entrez Gene
ROR1
GO Terms
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0005887 integral to plasma membrane
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0006468 protein phosphorylation
GO:0017147 Wnt-protein binding
Request a different product with this specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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