PPP2R5E antibody | IJ01-4C1
Mouse anti Human PPP2R5E
- Product Type
- Monoclonal Antibody
- Clone
- IJ01-4C1
- Isotype
- IgG1
- Specificity
- PPP2R5E
Antibody Quality and Performance Guarantee
| Mouse anti human PPP2R5E antibody, clone IJ01-4C1 recognizes serine/threonine-protein phosphatase 2A 56-kDa regulatory subunit epsilon isoform, also known as PP2A B subunit isoform B'-epsilon or PP2A B subunit isoform B56-epsilon. PPP2R5E is a member of the phosphatase 2A (PP2A) regulatory subunit B family and functions as a tumor suppressor in human cancers. Studies have also revealed that there may be a correlation between polymorphisms in PP2A subunit genes, including the PPP2R5E gene, and increased risk of lung cancer (Yang et al. 2013). Studies have also shown that PPP2R5E may play a role in the proliferation and apoptosis of gastric cancer cells (Liu et al. 2014). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli-derived recombinant protein, aa 1-467 of human PPP2R5E
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1,000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Mouse anti Human PPP2R5E antibody detects a band of 50 kDa in HeLa cell lysates
- UniProt
- Q16537
- Entrez Gene
- PPP2R5E
- GO Terms
- GO:0000159 protein phosphatase type 2A complex
- GO:0005515 protein binding
- GO:0007165 signal transduction
- GO:0005737 cytoplasm
- GO:0008601 protein phosphatase type 2A regulator activity
- GO:0043231 intracellular membrane-bounded organelle
MCA6416GA
100007681
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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