Osteocalcin antibody | 6F9G4E10

Osteocalcin (Bone Gla Protein) is a 49 amino acid ~5.8 kDa single chain vitamin K dependent protein, made by osteoblasts and major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget’s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Bovine Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3) - Carrier Free
- Yes
- Immunogen
- Recombinant human osteocalcin GST fusion protein.
- Approx. Protein Concentrations
- 1.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P02818
- Entrez Gene
- BGLAP
- GO Terms
- GO:0005509 calcium ion binding
- GO:0007155 cell adhesion
- GO:0008147 structural constituent of bone
- GO:0030282 bone mineralization
- GO:0030500 regulation of bone mineralization
- GO:0042476 odontogenesis
- GO:0045124 regulation of bone resorption
- GO:0045670 regulation of osteoclast differentiation
- GO:0046848 hydroxyapatite binding
- Regulatory
- For research purposes only
Applications of Osteocalcin antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA |
Secondary Antibodies Available
Product Specific References
References for Osteocalcin antibody
-
Gindraux, F.
(2010) Industrial approach in developing an advanced therapy product for bone repair.
J Tissue Eng Regen Med. 4: 194-204. -
Hellman, J. et al. (2004) Isolated osteocalcin fragments
US Patent Application: US20040259167A1
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