LAMTOR4 antibody | EF01-1D8
Mouse anti Human LAMTOR4
- Product Type
- Monoclonal Antibody
- Clone
- EF01-1D8
- Isotype
- IgG2a
- Specificity
- LAMTOR4
Antibody Quality and Performance Guarantee
| Mouse anti human LAMTOR4, clone EF01-1D8 recognizes the Ragulator complex protein LAMTOR4, also known as C7orf59. LAMTOR4 is a part of the Ragulator complex, which is an important regulator of cell metabolism and growth via the activation of the mTOR complex-1 pathway. (Bar-Peled et al. 2012). Deregulation within the mTORC1 pathway can be seen to result in conditions such as cancer, obesity and type 2 diabetes. The Ragulator complex in line with heterodimeric GTPases and the v-ATPase form a system that is used as an amino acid sensing system by mTORC1 (Bar-Peled & Sabatiniet al. 2014). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli-derived recombinant protein, aa 1-99 of human LAMTOR4
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Mouse anti Human LAMTOR4 antibody detects a band of 12 kDa in LNCaP cell lysates
MCA6420GA
100007685
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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